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Table 4 Tabulation of all ALDH genes in this study that show evidence of gene duplication, compared with that in the human genome

From: Update on the aldehyde dehydrogenase gene (ALDH) superfamily

Species Recommended gene name RefSeq Protein ID Protein length Ka/Ks Aligned sequences % AA (unaligned) % AA Identity (unaligned included) % AA Identity (unaligned excluded) Functional protein Recommended protein name
Cow ALDH1A3 XP_583647.3 537 0.234 - - - - Yes ALDH1A3
  ALDH1A3P1 XP_001789867.1 127 0.260 (a)/(b) 76.4 23.6 100 No Pseudogene
Zebrafish aldh2.1 NP_956784.1 516 0.278 - - - - Yes Aldh2.1
  aldh2.2 NP_998466.2 516 0.112 (a)/(b) 0 95.2 95.2 Yes Aldh2.2
  aldh2.3 XP_002662252.1 516 0.041 (a)/(c) 0 95.2 95.2 Yes Aldh2.3
      (b)/(c) 0 99.6 99.6 - -
Zebrafish aldh3a2.1 NP_997814.1 488 0.175 - - - - Yes Aldh3a2.1
  aldh3a2.2 XP_001335979.2 489 0.402 (a)/(b) 1.8 63.1 64.9 Yes Aldh3a2.1
  aldh3a2.3 XP_002666107.1 514 0.175 (a)/(c) 5.1 65.8 70.9 Yes Aldh3a2.3
  aldh3a2p1 NP_001004658.1 169 0.190 (a)/(d) 65.6 23.5 89.1 No Pseudogene
      (b)/(c) 7.5 57.4 64.9 - -
      (b)/(d) 66 18.9 84.9 - -
      (c)/(d) 67.1 31.3 98.4 - -
Zebra finch ALDH3A2 XP_002198810.1 510 0.396 - - - - Yes ALDH3A2
  ALDH3A3 XP_002196134.1 526 0.625 (a)/(b) 5.6 84.1 89.7 Yes ALDH3A3
Cow ALDH3B1 NP_001068986.1 486 0.335 - - - - Yes ALDH3B1
  ALDH3B4 XP_585724.2 486 0.550 (a)/(b) 4.5 80.9 85.4 Yes ALDH3B4
Zebra finch ALDH3B1 XP_002196917.1 450 0.308 - - - - Yes ALDH3B1
  ALDH3B5 XP_002196928.1 341 0.434 (a)/(b) 39.9 53.2 93.1 Yes ALDH3B5
Rat Aldh3b2 XP_001068348.2 483 0.436 - - - - Yes ALDH3B2
  Aldh3b3 XP_001068253.1 530 0.239 (a)/(b) 11 76.9 87.9 Yes ALDH3B3
Mouse Aldh3b2 NP_001170909.1 479 0.270 - - - - Yes ALDH3B2
  Aldh3b3 XP_900106.1 479 0.229 (a)/(b) 0 86.4 86.4 Yes ALDH3B3
Zebrafish aldh5a1.1 NP_001103938.1 404 < 0.001 - - - - Yes Aldh5a1.1
  aldh5a1.2 XP_002664997.1 514 0.008 (a)/(b) 21.4 78.6 100 Yes Aldh5a1.2
Macaque ALDH7A1 XP_002804539.1 502 0.180 - - - - Yes ALDH7A1
  ALDH7A1P5 XP_001111963.1 538 1.289 (a)/(b) 16.3 82.3 98.6 No Pseudogene
Zebrafish aldh9a1.1 NP_958879.1 508 0.126 - - - - Yes Aldh9a1.1
  aldh9a1.2 NP_958916.1 518 0.154 (a)/(b) 1.9 71.2 73.1 Yes Aldh9a1.2
  aldh9a1.3 NP_001119952.1 508 0.190 (a)/(c) 0 94.9 94.9 Yes Aldh9a1.3
      (b)/(c) 1.9 70.3 72.2 - -
Zebrafish aldh18a1.1 NP_001077015.1 782 0.103 - - - - Yes Aldh18a1.1
  aldh18a1.2 XP_002664020.1 782 0.826 (a)/(b) 0 100 100 Yes Aldh18a1.2
  1. Included are protein lengths (in number of amino acids [AAs]), Ka/Ks values, RefSeq protein IDs and recommended protein names. '% AA identity' denotes the absolute number of identical AAs relative to the absolute number of AA locations. '% AA unaligned' indicates the percentage of AAs that are represented by either a gap in the alignment of either sequence or an overhang if one sequence is longer than the other. '% AA identity (unaligned excluded)' indicates the percentage of AA locations that are identical when unaligned AAs are excluded from the total number of AA locations. For example, a 127-AA fragment of a 537-AA protein, which is identical except for the truncation, would have 127/537 = 23.6 per cent identity, of which 410/537 = 76.4 per cent is represented by unaligned residues (AAs in the longer sequence that have no correlation with the shorter sequence) but, excluding those residues, 127/127 = 100 per cent paired AAs are identical. The final column indicates which sequences are being compared for percentage identity, percentage gaps and percentage identity (excluding gaps)