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Table 7 Comparison of 13-SNP model with and without demographic factors

From: Clinical validation of a genetic model to estimate the risk of developing choroidal neovascular age-related macular degeneration

Step

Model

ROC

area

Standard

error

Confidence

limits

Training

Age +Sex +13 SNP

0.82

0.01

0.79-0.85

Training

13 SNP

0.82

0.01

0.79-0.85

Validation

Age +Sex +13 SNP

0.80

0.02

0.77-0.83

Validation

13 SNP

0.80

0.02

0.77-0.83

  1. There is no significant difference between the two models
  2. ROC, receiver operating characteristic; SNP, single nucleotide polymorphism
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Human Genomics

ISSN: 1479-7364