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Table 6 Nature of β-catenin gene in seven colorectal cancer patients from the Kashmir valley

From: Analysis of molecular aberrations of Wnt pathway gladiators in colorectal cancer in the Kashmiri population

Patient ID

Mutationa

Amino acid change

Affected codon

Effect

A1

GAC > GGC

Asp > Gly

32

MS

A5

AAA > TAA

Lys > Stop

49

NS

A9

AAA > TTA

Lys > Leu

49

MS

A10

GAC > GGC

Asp > Gly

32

MS

A62

AAA > TAA

Lys > Stop

49

NS

A74

GAC > GGC

Asp > Gly

32

MS

A82

TCT > TTT

Ser > Phe

45

MS

  1. aMutated, deleted or inserted nucleotide underlined.
  2. Abbreviations: MS, missense mutation; NS, nonsense mutation.