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Table 8 Correlation of APC mutation status versus APC methylation status

From: Analysis of molecular aberrations of Wnt pathway gladiators in colorectal cancer in the Kashmiri population

  APCstatus OR; 95% CI; pvalue
  Wild-type
W = 75
Mutanta
M = 11
 
APC promoter methylation b    
Unmethylated; n = 39 32 (42.7%) 7 (63.6%) 2.35; 0.63-8.72; 0.22
Methylated; n = 47 43 (57.3%) 4 (36.4%)  
  1. aOther than G > A transition at codon 1492.
  2. bEither 1A or 1B promoter hypermethylation.
  3. Abbreviations: OR, odds ratio; CI, confidence interval.