Table 4 Association between CYP2E1 (RsaI) polymorphism and clinicopathological characteristics
From: Role of CYP2E1 genotypes in susceptibility to colorectal cancer in the Kashmiri population
Variables | Â | Â | Cases (n= 86) | Â | Â |
|---|---|---|---|---|---|
|  | n= 86 | c1/c1 46 (53.5%) | c1/c2 15 (17.4%) | c2/c2 25 (29.1%) | χ2; pvalue |
Age group | Â | Â | Â | Â | Â |
≤ 50 | 30 (34.9%) | 21 | 5 | 4 | 6.29; 0.04 |
> 50 | 56 (65.1%) | 25 | 10 | 21 | Â |
Gender | Â | Â | Â | Â | Â |
Female | 37 (43.0%) | 20 | 6 | 11 | 0.07; 0.96 |
Male | 49 (67.0%) | 26 | 9 | 14 | Â |
Dwelling | Â | Â | Â | Â | Â |
Rural | 59 (68.6%) | 27 | 11 | 21 | 5.0; 0.08 |
Urban | 27 (31.4%) | 19 | 4 | 4 | Â |
Smoking status | Â | Â | Â | Â | Â |
Ever | 55 (64.0%) | 29 | 8 | 18 | 1.45; 0.48 |
Never | 31 (36.0%) | 17 | 7 | 7 | Â |
Tumour location | Â | Â | Â | Â | Â |
Colon | 36 (41.9%) | 19 | 5 | 12 | 0.84; 0.65 |
Rectum | 50 (58.1%) | 27 | 10 | 13 | Â |
Nodal status | Â | Â | Â | Â | Â |
Involved | 48 (55.8%) | 24 | 4 | 20 | 11.34; 0.003 |
Not Involved | 38 (44.2%) | 22 | 11 | 5 | Â |
Tumour grade | Â | Â | Â | Â | Â |
A + B | 38 (44.2%) | 22 | 11 | 5 | 11.34; 0.003 |
C + D | 48 (55.8%) | 24 | 4 | 20 | Â |
Pesticide exposure | Â | Â | Â | Â | Â |
Ever | 53 (61.6%) | 26 | 8 | 19 | 3.13; 0.20 |
Never | 33 (38.4%) | 20 | 7 | 6 | Â |
Bleeding PR/constipation | Â | Â | Â | Â | Â |
Yes | 60 (69.8%) | 32 | 10 | 18 | 0.13; 0.93 |
No | 26 (30.2%) | 14 | 5 | 7 | Â |
Tumour type a | Â | Â | Â | Â | Â |
Mucinous | 33 (38.5%) | 20 | 6 | 7 | 1.84; 0.39 |
Non-mucinous | 52 (60.5%) | 25 | 9 | 18 | Â |