Table 5 Association between CYP2E1 (96 bp) polymorphism and clinicopathological characteristics
From: Role of CYP2E1 genotypes in susceptibility to colorectal cancer in the Kashmiri population
Variables | Â | Â | Cases (n= 86) | Â | Â |
|---|---|---|---|---|---|
|  | n= 86 | i/i 55 (63.9%) | i/I 19 (22.1%) | I/I 12 (13.9%) | χ2; pvalue |
Age group | Â | Â | Â | Â | Â |
≤ 50 | 30 (34.9%) | 19 | 7 | 4 | 0.05; 0.97 |
> 50 | 56 (65.1%) | 36 | 12 | 8 | Â |
Gender | Â | Â | Â | Â | Â |
Female | 37 (43.0%) | 26 | 8 | 3 | 2.0; 0.36 |
Male | 49 (67.0%) | 29 | 11 | 9 | Â |
Dwelling | Â | Â | Â | Â | Â |
Rural | 59 (68.6%) | 38 | 13 | 8 | 0.03; 0.98 |
Urban | 27 (31.4%) | 17 | 6 | 4 | Â |
Smoking status | Â | Â | Â | Â | Â |
Ever | 55 (64.0%) | 35 | 10 | 10 | 3.01; 0.22 |
Never | 31 (36.0%) | 20 | 9 | 2 | Â |
Tumour location | Â | Â | Â | Â | Â |
Colon | 36 (41.9%) | 22 | 5 | 9 | 7.38; 0.02 |
Rectum | 50 (58.1%) | 33 | 14 | 3 | Â |
Nodal status | Â | Â | Â | Â | Â |
Involved | 48 (55.8%) | 28 | 12 | 8 | 1.53; 0.46 |
Not Involved | 38 (44.2%) | 27 | 7 | 4 | Â |
Tumour grade | Â | Â | Â | Â | Â |
A + B | 38 (44.2%) | 27 | 7 | 4 | 1.53; 0.46 |
C + D | 48 (55.8%) | 28 | 12 | 8 | Â |
Pesticide exposure | Â | Â | Â | Â | Â |
Ever | 53 (61.6%) | 38 | 9 | 6 | 3.62; 0.16 |
Never | 33 (38.4%) | 17 | 10 | 6 | Â |
Bleeding PR/constipation | Â | Â | Â | Â | Â |
Yes | 60 (69.8%) | 42 | 11 | 7 | 3.15; 0.20 |
No | 26 (30.2%) | 13 | 8 | 5 | Â |
Tumour type* | Â | Â | Â | Â | Â |
Mucinous | 33 (38.5%) | 22 | 7 | 4 | 0.27; 0.87 |
Non-mucinous | 52 (60.5%) | 32 | 12 | 8 | Â |