Table S1 Subject characteristics
Population | Mean age | Range | Standard deviation | % Male |
|---|---|---|---|---|
Massachusetts Eye and Ear Infirmary Extremely Discordant Sibling Pair Discovery Cohort (n= 270 individuals from 135 families) | ||||
Neovascular subjects (n = 135) | 71.7 | 49.0-85.5 | 8.0 | 47% |
Control subjects (n = 135) | 76.0 | 50.3-93.9 | 7.6 | 39% |
Massachusetts Eye and Ear Infirmary Cohort Extended Sibling Pair Cohort ( n = 657 individuals from 284 families) | ||||
Population | Mean age | Range | Standard deviation | % Male |
Neovascular subjects (n = 353) | 73.9 | 49.0-94.0 | 7.8 | 41% |
Dry subjects (n = 106) | 77.6 | 58.2-100.6 | 7.2 | 35% |
Control subjects (n = 198) | 75.4 | 50.3-94.3 | 8.3 | 44% |
Central Greece cohort ( n = 344 individuals) | ||||
Population | Mean age | Range | Standard deviation | % Male |
Neovascular subjects (n = 139) | 76.23 | 49.0-94.0 | 7.5 | 45% |
Dry subjects (n = 84) | 74.52 | 52.0-91.0 | 7.8 | 44% |
Control subjects (n = 121) | 73.53 | 48.0-88.0 | 7.3 | 51% |
Prospective-based cohort derived from the Nurses' Health Study/Health Professionals Study ( n = 1,527 individuals) | ||||
Population | Mean age | Range | Standard deviation | % Male |
Neovascular subjects (n = 164) | 61.1 | 42.7-74.0 | 6.0 | 46% |
Dry subjects (n = 293) | 59.5 | 41.3-74.0 | 5.7 | 18% |
Control subjects (n = 1070) | 60.2 | 41.3-74.0 | 5.9 | 36% |