Table 1 Genotype distributions and allele frequencies of the four polymorphisms in athletes and control groups
From: Association of genome variations in the renin-angiotensin system with physical performance
Male controls | Male athletes | pvalue | Female controls | Female athletes | pvalue | ||
|---|---|---|---|---|---|---|---|
(n= 88) | (n= 102) | (n= 83) | (n= 73) | ||||
Genotype distributions | |||||||
ACE | II | 12 (13.64%) | 7 (6.86%) | 0.121 | 14 (16.87%) | 13 (17.81%) | 0.877 |
ID | 45 (51.14%) | 60 (58.82%) | 0.288 | 43 (51.81%) | 25 (34.25%) | 0.027 | |
DD | 31 (35.23%) | 35 (34.31%) | 0.859 | 26 (31.33%) | 35 (47.95%) | 0.034 | |
AGTR1 (A +1166 C) | AA | 53 (60.23%) | 57 (55.88%) | 0.545 | 45 (54.22%) | 41 (56.16%) | 0.807 |
AC | 32 (36.36%) | 39 (38.24%) | 0.79 | 35 (42.17%) | 26 (35.62%) | 0.403 | |
CC | 3 (3.41%) | 6 (5.88%) | 0.424 | 3 (3.61%) | 6 (8.22%) | 0.218 | |
BDKRB2 (+9/−9) | (+9/+9) | 30 (34.09%) | 33 (32.35%) | 0.757 | 24 (28.92%) | 20 (27.40%) | 0.833 |
(+9/−9) | 46 (52.27%) | 58 (56.86%) | 0.53 | 45 (54.22%) | 45 (61.64%) | 0.349 | |
(−9/−9) | 12 (13.64%) | 11 (10.78%) | 0.528 | 14 (16.87%) | 8 (10.96%) | 0.29 | |
LEP (G–2548A) | AA | 16 (18.18%) | 19 (18.63%) | 0.937 | 12 (14.46%) | 15 (20.55%) | 0.297 |
GA | 46 (57.27%) | 58 (56.86%) | 0.526 | 46 (55.42%) | 41 (56.16%) | 0.926 | |
GG | 26 (29.55%) | 25 (24.51%) | 0.435 | 25 (30.12%) | 17 (23.29%) | 0.363 | |
Allele frequencies | |||||||
I allele (ACE gene) | 57 (64.8%) | 67 (65.7%) | 0.895 | 57 (68.7%) | 38 (52.1%) | 0.034 | |
D allele (ACE gene) | 76 (86.4%) | 95 (93.1%) | 0.121 | 69 (83.1%) | 60 (82.2%) | 0.877 | |
A allele (AGRT1 gene) | 85 (96.6%) | 96 (94.1%) | 0.424 | 80 (96.4%) | 67 (91.8%) | 0.218 | |
C allele (AGRT1 gene) | 35 (39.8%) | 45 (44.1%) | 0.545 | 38 (45.8%) | 32 (43.8%) | 0.807 | |
+9 allele (BDKRB2 gene) | 76 (86.4%) | 91 (89.2%) | 0.548 | 69 (83.1%) | 65 (89%) | 0.29 | |
−9 allele (BDKRB2 gene) | 58 (65.9%) | 69 (67.6%) | 0.800 | 59 (71.1%) | 53 (72.6%) | 0.833 | |
A allele (LEP gene) | 62 (70.5%) | 77 (75.5%) | 0.435 | 58 (69.9%) | 56 (76.7%) | 0.337 | |
G allele (LEP gene) | 72 (81.8%) | 83 (81.4%) | 0.937 | 71 (85.5%) | 58 (79.5%) | 0.316 | |