Figure 3

Phylogenetic tree of the human βγ-crystallin gene superfamily. Sequences were extracted from the UCSC web browser. Translated ORFs were aligned and neighbor-joining trees were constructed as in Figure 2. AIM1, AIML, and CRYBG3 contain internal repeats corresponding to three β-crystallin-like genes in addition to regions not related to crystallin genes. For simplicity, the third, most highly conserved crystallin repeat from each gene was used for this alignment (designated AIM1cter, etc.).