Skip to main content
Figure 2 | Human Genomics

Figure 2

From: CXCL5 polymorphisms are associated with variable blood pressure in cardiovascular disease-free adults

Figure 2

Allele-specific CXCL5 mRNA expression in leukocytes. (A) Allelic mRNA and DNA ratios were measured in 18 cardiovascular disease-free individuals heterozygous for the 398 G > A SNP. The A/G ratios in DNA were close to 1 suggesting equal abundance of both alleles, whereas there was consistently higher expression of mRNA from the 398A allele compared to the 398 G allele. (B) Pooled 398A/G ratios from 18 heterozygous individuals. The sample displayed 2.9-fold higher expression of 398A variant transcripts compared to the 398 G allele (P = 7.4E-15). Data are presented as mean ± SD

Back to article page

Human Genomics

ISSN: 1479-7364