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Table 1 Summary of genes and SNPs identified by meta-analysis to be positively correlated with various cancers

From: Comparative study and meta-analysis of meta-analysis studies for the correlation of genomic markers with early cancer detection

Gene Cancer type SNPs References Supporting references
   rs number Other name   
ERCC2 BC rs13181 p.K715Q [12, 13] [1417]
ERCC2 BC rs1799793 p.D312N [12, 18] [1416]
ERCC2 LC rs13181 p.K751Q [19, 20] [17, 21, 22]
ERCC2 LC rs1799793 p.D312N [23] [17, 21, 22]
CCND1 BC rs603965 c.870G>A [24] [2531]
CYP2E1 CRC rs3813867 NA [32] [3241]a
CYP2E1 HNC rs3813867 NA [42, 43] [44]
CYP2E1 HNC rs6413432 NA [42] [44]
GSTP1 CRC rs1695 p.I105V [45] [39, 4655]
IL6 BC rs1800795 c.-174G>C [56, 57]  
MTHFR GC rs1801131 c.1298A>C [58] [59, 60]b
MTHFR BC rs1801131 c.677C>T, c.1298A>C [61, 62] [63, 64]
SOD2 BC rs4880 p.V16A, p.A9V [62, 65, 66]  
TGFB1 BC rs1800469 NA [6769]  
TGFB1 BC rs1800470 NA [67, 7073]  
TGFB1 BC rs1982073 NA [74] [64, 7577]
TP53 BC rs1042522 p.R72P [78, 79] [8094]
TP53 UBC rs1042522 p.R72P [95] [96100]
TP53 CRC rs1042522 p.R72P [78, 101103] [104108]
TP53 CRC rs17878362 NA [78] [104108]
TP53 EC rs1042522 p.R72P [109, 110] [111]
TP53 LC rs1042522 p.R72P [78] [112117]
TP53 LC rs17878362 NA [78] [112117]
VEGFA BC rs3025039, rs699947 c.936C>T, c.-2578C>A [20, 45, 118, 119] [120]
  1. These findings are supported by the published literature. aFor a different SNP (rs1329149); bfor c.677C>T and c.1298A>C. NA not available.