Table 3 Putative gene-gene associations with various cancer types
Gene associations | Considered phenotypes | Comments | STRING confirmation | Literature confirmation | |
|---|---|---|---|---|---|
Gene 1 | Gene 2 | Â | Â | Â | Â |
GSTP1 | GSTM1 | 4 | Â | Binding interaction | [Reference]: study type |
TGFB1 | IL6 | 5 | 4 of 5 based on ‘yes’ |  |  |
MMP2 | EGF | 3 | Based on ‘yes’ | Activating interaction |  |
VEGFA | IL1B | 2 | Â | Activating interaction | Â |
MMP9 | IL8 | 4 | Based on ‘may’ | Activating interaction | KEGG: same process |
MMP1 | MMP3 | 5 | Based on ‘may’ |  |  |