Skip to main content
Figure 7 | Human Genomics

Figure 7

From: Rank-based genome-wide analysis reveals the association of Ryanodine receptor-2 gene variants with childhood asthma among human populations

Figure 7

Work flow diagram. For each population, single-SNP analysis was first conducted using the family-based TDT. SNPs were then mapped to genes, and genes were mapped to pathways/gene sets based on annotation databases. Pathway level associations with childhood asthma were obtained based on gene set analysis. Overlapping and population-specific top-ranked genetic risk factors across the three populations at the locus and pathway levels were studied to investigate shared or unique pathophysiological processes in the study population.

Back to article page

Human Genomics

ISSN: 1479-7364