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Table 8 Top diseases and disorders related to the 11 genes shared among the top 1,000 SNPs across populations

From: Rank-based genome-wide analysis reveals the association of Ryanodine receptor-2 gene variants with childhood asthma among human populations

    Functions

pvalues

Genes

Cardiovascular disease

1.90 × 10−5–3.86 × 10−2

CDH13, CSMD1, PDE4D, RBFOX1, RYR2

Genetic disorder

1.90 × 10−5–4.21 × 10−2

CDH13, CSMD1, PDE4D, RBFOX1, RYR2, ROBO2, NPAS3, SEMA5A

Hematological disease

1.90 × 10−5–1.63 × 10−2

CDH13, CSMD1, PDE4D, RBFOX1, RYR2

Psychological disorders

7.15 × 10−4–3.45 × 10−2

NPAS3, RBFOX1, SEMA5A, PDE4D

Inflammatory disease

1.16 × 10−3–4.21 × 10−2

NPAS3, PDE4D, RYR2

Respiratory disease

1.16 × 10−3–2.05 × 10−2

NPAS3, PDE4D