Figure 1From: Role of conserved cis-regulatory elements in the post-transcriptional regulation of the human MECP2 gene involved in autismThe G-quadruplex map of MECP2 mRNA orthologs. The 5′-UTR and CDS region G-quadruplexes are conserved in terms of their relative location to the translation start site in the MECP2 mRNA orthologs. Based on their observed conservation level, G-quadruplexes have been categorized into groups. Location conserved G-quadruplexes ‘CG’ (in the 5′-UTR), ‘X,’ ‘Y,’ and ‘Z’ (in the CDS) were subjected to further sequence analysis.Back to article page