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Figure 1 | Human Genomics

Figure 1

From: Role of conserved cis-regulatory elements in the post-transcriptional regulation of the human MECP2 gene involved in autism

Figure 1

The G-quadruplex map of MECP2 mRNA orthologs. The 5′-UTR and CDS region G-quadruplexes are conserved in terms of their relative location to the translation start site in the MECP2 mRNA orthologs. Based on their observed conservation level, G-quadruplexes have been categorized into groups. Location conserved G-quadruplexes ‘CG’ (in the 5′-UTR), ‘X,’ ‘Y,’ and ‘Z’ (in the CDS) were subjected to further sequence analysis.

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