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Table 2 Association of CER1 genotypes with T -score and multiple logistic regression analysis for fracture prediction

From: CER1gene variations associated with bone mineral density, bone markers, and early menopause in postmenopausal women

CER1genotypes

Total cohort

Osteoporotic patients

 

T-score

Vertebral fracture

Hip fracture

Any fracture

 

Mean

SD

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

rs3747532: (C/C)

−1.1

1.6

<0.05

1.71 (0.2–3.13)

NS

1.63 (0.76–3.48)

NS

1.79 (0.79–4.09)

NS

(C/G), (G/G)

−2.0

1.0

rs1494360: (G/G)

−1.1

1.4

<0.05

2.12 (0.23–13.54)

NS

1.98 (0.3–23.22)

<0.05

1.38 (0.49–15.5)

<0.01

G/T), (T/T)

−2.4

1.1

rs7022304: (A/A)

−1.1

1.5

<0.05

0.90 (0.23–3.49)

NS

1.22 (0.49–3.01)

NS

1.47 (0.49–8.1)

NS

(A/G), (G/G)

−2.2

1.2

rs17289263: (A/A)

−1.0

1.4

<0.05

1.55 (0.42–5.04)

NS

1.15 (0.48–2.75)

NS

2.18 (0.61–5.2)

NS

(A/G), (G/G)

−2.2

1.2

rs74434454: (T/T)

−1.0

1.5

<0.05

1.13 (0.46–3.72)

NS

1.90 (0.34–10.56)

NS

1.98 (0.3–13.22)

NS

(T/C), (C/C)

−2.2

1.1

       
  1. Significant values are shown in italics; NS not significant.
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