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Table 4 Association of GATA4 haplotypes with metabolic disease risk traits

From: A study of the role of GATA4 polymorphism in cardiovascular metabolic disorders

 

Controls

Cases

 

All

Male

Female

All

Male

Female

Gender

2,004

1,074 (53.6)

930 (46.4)

2,274

1,736 (76.3)

538 (23.7)

Age

50.2 ± 0.5

50.81 ± 0.5

49.66 ± 0.5

60.8 ±0.4

59.7 ± 0.3

61.8 ± 0.5

BMI

29.4 ±0.2

28.01 ± 0.2

30.69 ± 0.2

29.7 ± 0.2

28.3 ± 0.1

31.1 ± 0.3

MI

1,388

684 (0.49)

704 (0.51)

2,890

2,126 (0.74)

764 (0.26)

T2DM

1,900

1,220 (0.64)

680 (0.36)

2,378

1,590 (0.67)

788 (0.33)

HTN

966

650(0.67)

314 (0.33)

3,312

2,158 (0.65)

1,154 (0.35)

lHDLC

2,209

1,262 (0.57)

947 (0.43)

1,776

1,371 (0.77)

405 (0.23)

hLDL

3,404

2,267 (0.67)

1,137 (0.33)

575

364 (0.63)

211 (0.37)

hTG

2,896

1,859 (0.64)

1,037 (0.36)

1,088

773 (0.71)

315 (0.29)

hChol

2,487

1,639 (0.66)

848 (0.34)

1,590

1,051 (0.66)

539 (0.34)

CHD

4,128

2,741 (0.66)

1,387 (0.34)

150

69 (0.46)

81 (0.54)

FH

3,421

2,255 (0.66)

1,166 (0.34)

857

555 (0.65)

302 (0.35)

OBS

2,362

1,729 (0.73)

633 (0.27)

1,631

895 (0.55)

736 (0.45)

Smokers

2,575

1,223 (0.47)

1,352 (0.53)

1,619

1,547 (0.96)

72 (0.04)

VD

      

 One

0

0

0

847

614 (0.72)

233 (0.28)

 Two

0

0

0

456

355 (0.78)

101 (0.22)

 More than two

0

0

0

971

767 (0.79)

204 (0.21)

  1. The numbers in brackets give the percentages of the total (all) values of the group. BMI, body mass index; CHD, congenital heart disease; FH, family history of CAD; MI, myocardial infarction; lHDLC, low high-density lipoprotein-cholesterol level; hTG, hypertriglyceridaemia; hChol, hypercholesterolaemia; HTN, hypertension; T2DM, type 2 diabetes mellitus; VD, number of diseased vessels.