Figure 2From: Genetic effects of ATP1A2 in familial hemiplegic migraine type II and animal modelsThree separate groups have mutated the Atp1a2 gene in mice. Two groups created knock-outs through disruption of the gene at two different locations and the other has created a knock-in mutation to mimic one of the FHM2 mutations in exon 19. Atp1a2 is located in the antisense strand of chromosome 1 [18, 19, 26].Back to article page