Table 5 The diseases associated to CD-SNVs and small indels
Disease name | p value | Number of genes associated | Number of variances found | Tumour tissue | Control tissue |
|---|---|---|---|---|---|
CD-SNVs | |||||
Cancer | 7.04E-23 | 111 | 202 | 1 | 1 |
Tumourigenesis | 8.21E-16 | 111 | 202 | 1 | 1 |
Cancers and tumours | 3.37E-15 | 111 | 202 | 1 | 1 |
Organismal injury and abnormalities | 9.45E-17 | 105 | 194 | 1 | 1 |
Carcinoma | 3.46E-25 | 99 | 186 | 1 | 1 |
Solid tumour | 2.64E-24 | 99 | 186 | 1 | 1 |
Epithelial neoplasia | 3.34E-23 | 99 | 186 | 1 | 1 |
Epithelioma | 3.34E-23 | 99 | 186 | 1 | 1 |
Breast or colorectal cancer | 5.45E-23 | 83 | 164 | 1 | 1 |
Malignant neoplasm of abdomen | 6.93E-20 | 83 | 169 | 1 | 1 |
Bone marrow cancer | 1.69E-03 | 15: CREBBP, EPHA2, FGFR2, KCNJ12, KMT2C, LILRB3, MUC17, MUC4, MYBPC3, NPM1, RARA, SMO, TCF3, TTN, TUBG1 | 43 | 1 | 0 |
Bone marrow cancer and tumours | 1.69E-03 | 43 | 1 | 0 | |
Small indels | |||||
Cancer | 9.07E-03 | 6 | 6 | 1 | 1a |
Hematologic cancer | 2.36E-04 | 4 | 4 | 1 | 1a |
Hematologic cancer and tumours | 2.36E-04 | 4 | 4 | 1 | 1a |
Hematological neoplasia | 8.01E-04 | 4 | 4 | 1 | 1a |
Lymphohematopoietic cancer | 9.12E-04 | 4 | 4 | 1 | 1a |
Disease of colon | 7.88E-03 | 4 | 4 | 1 | 0 |
Hematological disease | 8.15E-03 | 4 | 4 | 1 | 1a |
Immunological disease | 1.28E-02 | 4 | 4 | 1 | 1a |
Gastrointestinal tract cancer | 2.00E-02 | 4 | 4 | 1 | 0 |
Gastrointestinal tract cancer and tumours | 2.02E-02 | 4 | 4 | 1 | 0 |
Tumourigenesis of bone tumour | 7.04E-03 | 1: ALK | 1 | 1 | 0 |