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Table 2 The top 20 genes identified as being significantly differentially expressed between MPNSTs and PNFs in the more stringent analysis of 3 vs. 3 samples

From: Evaluation of copy number variation and gene expression in neurofibromatosis type-1-associated malignant peripheral nerve sheath tumours

Transcript ID Gene symbol Ref seq Mean expression Mean expression Fold change P value Chromosome Start Stop
    Benign Malignant Benign vs. malignant Benign vs. malignant  
2584134 FAP NM_004460 4.87 8.75 14.75 0.0001 2 163027200 163101589
4013828 NSBP1 NM_030763 5.22 3.67 −2.92 0.0001 X 80211860 80457431
3917555 KRTAP13n4 NM_181600 3.77 3.13 −1.55 0.0001 21 31797943 31809269
3908934 PTGIS NM_000961 4.58 6.60 4.06 0.0002 20 48120414 48185550
2764192 KIAA0746 NM_015187 4.33 5.82 2.80 0.0002 4 25722248 25865344
2735027 SPP1 NM_001040058 5.65 12.06 85.19 0.0002 4 88408243 88904561
3532353 FAM177A1 NM_001079519 8.01 7.11 −1.86 0.0003 14 35508201 35582327
2779231 ADH1B NM_000668 6.50 3.18 −9.99 0.0003 4 100226131 100242895
2406926 GRIK3 NM_000831 7.20 3.85 −10.19 0.0004 1 37266614 37524753
3916290 FLJ42200 AK124194 3.32 4.05 1.65 0.0004 21 25353415 25920256
2970942 COL10A1 NM_000493 3.56 4.67 2.17 0.0004 6 116440092 116518549
2450865 CSRP1 NM_004078 9.09 7.28 −3.50 0.0005 1 201445919 201481500
2918982 GRIK2 NM_175768 7.02 3.47 −11.66 0.0005 6 101841683 102690448
3204648 CD72 NM_001782 4.08 5.08 1.99 0.0005 9 35609970 35646790
4006326 EFHC2 NM_025184 4.84 3.42 −2.67 0.0005 X 44006888 44309044
2586845 SLC25A12 NM_003705 5.56 6.30 1.68 0.0006 2 172639117 172750960
2579439 GTDC1 NM_001006636 6.95 5.92 −2.05 0.0006 2 144702190 145123135
3872053 PEG3 NM_006210 5.58 4.17 −2.65 0.0006 19 57285930 57352082
2801526 CCT5 NM_012073 8.62 9.33 1.64 0.0006 5 10250111 10266501
3548152 TDP1 NM_018319 4.17 5.49 2.50 0.0007 14 90421293 90511103
  1. The top 20 genes identified as being significantly differentially expressed between MPNSTs and PNFs in the more stringent analysis of 3 vs. 3 samples.