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Table 3 Epigenetic heredity of cancer-causing genes

From: Epigenetic inheritance and the missing heritability

Bladder Aberrant methylation of TWIST, NID2, and RUNX3
Brain Aberrant methylation of RASSF1A and MGMT
Breast Aberrant methylation of BRCA1, Sat-2, IGF2, ATM, RASSF1A, and other genes
Cervix Hypermethylation of CDKN2A/p16
Colon-Rectum Aberrant methylation of MHL1, SEPT9, IGF2, THBD, C9orf50, and other genes
Esophagus Aberrant methylation of CDH1, PIGR, RIN2, and other genes
Head/Neck Hypermethylation of CDKN2A/p16 and MGMT
Kidney Hypermethylation of TIMP-3
Leukemia Hypermethylation of p15 and chromosomal translocations involving HATs and HMTs
Liver Aberrant methylation of multiple genes
Lung Hypermethylation of CDKN2A/p16, p73, RARb, RASSF1A, GSTP1, MGMT, and other genes
Lymphoma/Myeloma Hypermethylation of DAPK
Ovary Hypermethylation of BRCA1 and hypomethylation of SAT2
Pancreas Hypermethylation of APC and hypomethylation of other genes
Prostate Hypermethylation of BRCA2
Rhabdomyosarcoma Hypermethylation of PAX3
Stomach Hypomethylation of Cyclin D2
Thymus Hypomethylation of POMC
Urothelial Hypomethylation of Satellite DNA
Uterus Hypermethylation of hMLH1 leading to Microsatellite instability