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Fig. 4 | Human Genomics

Fig. 4

From: Integrative DNA methylation and gene expression analysis to assess the universality of the CpG island methylator phenotype

Fig. 4

Mutation analysis. a Association between specific mutations (IDH1, IDH2, BRAF, and KRAS) with the CIMP phenotype for all tissues (yellow = CIMP positive, blue = CIMP negative). b Significantly higher mutation rate for CIMP-positive (yellow) compared to CIMP-negative (blue) tumors is observed for colon and gastric cancers only and is concordant with CIMP association with microsatellite instability for these tissues

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Human Genomics

ISSN: 1479-7364