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Fig. 1 | Human Genomics

Fig. 1

From: Integrative genomic analysis reveals functional diversification of APOBEC gene family in breast cancer

Fig. 1

Expression of APOBEC3B and APOBEC3C genes in breast cancer cell lines and tissues in relation to ER status. a mRNA levels of APOBEC3B and APOBEC3C in breast cancer cell lines with ER subtypes and normal cell lines. b mRNA levels of APOBEC3B and APOBEC3C in breast tumor tissues with ER subtypes and adjacent normal tissues. c Comparison of chromatin states in APOBEC3 family genes in ER+ (MCF-7), ER− (HCC1954) breast cancer cells, and normal cells (HMEC). The highlight with rectangle is on APOBEC3B and APOBEC3C genes. Chromatin states characterized by the ChromHMM algorithm are represented by different colors shown in the bottom

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