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Fig. 2 | Human Genomics

Fig. 2

From: Intragraft transcriptional profiling of renal transplant patients with tubular dysfunction reveals mechanisms underlying graft injury and recovery

Fig. 2

Distribution of uRBP levels according to glomerular filtration rates and hierarchical clustering analysis of samples from different ranges of uRBP levels. a Histograms showing uRBP values according to eGFR levels at enrollment (t0) and after 12 months of follow-up (t12). uRBP levels are expressed as the mean ± SEM. The estimated glomerular filtration rates (eGFR) were calculated using the MDRD formula. **p < 0.05, **p < 0.001 compared to eGFR at 30–45 mL/min, using ANOVA followed by Tukey’s correction. b Best-fit slope of the linear regression of the delta values from urinary retinol-binding protein (uRBP) levels and eGFR between t0 and t12. The estimated eGFR was calculated using Cockcroft-Gault or MDRD formulas. c Hierarchical clustering analysis of samples in the high group (HG, uRBP levels from 0.4 to 1 mg/L) and very high group (VHG, uRBP ≥ 1 mg/L) at t0 and t12

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