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Table 2 Association between ABCA1 and CETP genotypes and alleles with CAD

From: The impact of common polymorphisms in CETP and ABCA1 genes with the risk of coronary artery disease in Saudi Arabians

SNP

Genotype/alleles

Cases (N = 990)

Control (N = 618)

OR (95 % CI)

P value

rs2230806 (R219K)

RR

291

195

Ref

RK

473

317

0.9 (0.79–1.25)

0.999

KK

226

106

1.42 (1.06–1.91)

0.017

RK+KK

699

423

1.10 (0.89–1.37)

0.359

R(G)

1055

707

Ref

K(A)

925

529

1.17 (1.01–1.35)

0.029

rs2066715 (V825I)

VV

945

597

Ref

VI

45

21

1.35 (0.79–2.29)

0.26

II

0

0

–

–

VI+II

45

21

1.35 (0.79–2.29)

0.26

V(G)

1935

1215

Ref

I(A)

45

21

1.34 (0.79–2.26)

0.27

rs5882 (V422I)

VV

178

147

Ref

VI

523

297

1.45 (1.12–1.88)

0.005

II

289

174

1.37 (1.02–1.82)

0.031

VI+II

812

471

1.42 (1.11–1.82)

0.005

V(G)

879

591

Ref

I(A)

1101

645

1.14 (0.99–1.32)

0.058

rs708272 (TaqIB)

B1B1

376

183

Ref

B1B2

454

321

0.68 (0.54–0.86)

0.001

B2B2

160

114

0.68 (0.50–0.92)

0.012

B1B2+B2B2

614

435

0.68 (0.55–0.85)

0.0006

B1(G)

1206

687

Ref

B2(A)

774

549

0.80 (0.69–0.92)

0.003