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Table 4 Association between ABCA1 and CETP genotypes and CAD in male and female cohorts

From: The impact of common polymorphisms in CETP and ABCA1 genes with the risk of coronary artery disease in Saudi Arabians

Genotype

Male cohort

Female cohort

Cases (n = 708)

Control (n = 423)

OR (95 % CI)

P value

Cases (n = 282)

Control (n = 195)

OR (95 % CI)

P value

R219K

RR

212

137

Ref

 

79

58

Ref

RK

337

229

0.95 (0.72–1.24)

0.718

136

88

1.13 (0.73–1.74)

0.566

KK

159

57

1.80 (1.24–2.61)

0.001

67

49

1.0 (0.60–1.65)

0.987

V825I

VV

676

414

Ref

 

269

183

Ref

VI

32

9

2.17 (1.02–4.60)

0.041

13

12

0.73 (0.32–1.65)

0.458

V422I

VV

123

103

Ref

 

55

44

Ref

VI

376

232

1.35 (0.99–1.84)

0.052

147

65

1.80 (1.10–2.96)

0.018

II

209

88

1.98 (1.38–2.85)

0.0002

80

86

0.74 (0.45–1.22)

0.246

TaqIB

B1B1

261

124

Ref

 

115

59

Ref

B1B2

340

247

0.65 (0.49–0.85)

0.002

114

74

0.79 (0.51–1.21)

0.282

B2B2

107

52

0.97 (0.65–1.45)

0.91

53

62

0.43 (0.27–0.71)

0.0008

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Human Genomics

ISSN: 1479-7364