Table 2 The best models identified by QMDR for COPD-related quantitative traits in Chinese Han population (n = 310 patients)

FEV₁

EPHX1(rs2292568)*GSTP1(rs4147581)

2.6390

7/10

0.019*

FEV₁%pre

EPHX1(rs1051741)*TGFB1(rs6957)

1.9234

7/10

0.042*

FVC

SERPINE2(rs7583463)*TGFB1(rs2241713)

2.2735

8/10

0.028*

FEV₁/FVC (%)

SERPINE2(rs17196253)*SERPINE2(rs6748795)

0.3566

3/10

NS

BODE

SERPINE2(rs4674841)*SERPINE2 (rs6748795)

−0.3295

4/10

NS

MMRC

SERPINE2(rs2118409)*SERPINE2 (rs6712954)

1.467

2/10

NS

6MWT

SERPINE2(rs7583463)*SERPINE2 (rs2118409)

1.229

7/10

NS