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Table 2 Top 20 up-regulated genes in periodontitis tissues

From: Transcriptome sequencing of gingival biopsies from chronic periodontitis patients reveals novel gene expression and splicing patterns

Ensemble ID

Gene symbol

Fold change

q value

Description

ENSG00000108342

CSF3

181.6

5.9E-21

Colony stimulating factor 3 (granulocyte)

ENSG00000182759

MAFA

157.5

8.2E-09

V-MAF avian musculoaponeurotic fibrosarcoma oncogene homolog A

ENSG00000117322

CR2

69.6

1.5E-07

Complement component (3D/Epstein Barr virus) receptor 2

ENSG00000178445

GLDC

50.8

2.6E-11

Glycine dehydrogenase (decarboxylating)

ENSG00000173432

SAA1

46.4

1.8E-14

Serum amyloid A1

ENSG00000129988

LBP

45.1

1.4E-05

Lipopolysaccharide binding protein

ENSG00000196549

MME

45.0

1.2E-14

Membrane metallo-endopeptidase

ENSG00000149968

MMP3

39.6

7.1E-10

Matrix metallopeptidase 3 (stromelysin 1, progelatinase)

ENSG00000240666

MME-AS1

38.8

2.1E-09

MME antisense RNA 1

ENSG00000148965

SAA4

37.3

4.7E-06

Serum amyloid A4, constitutive

ENSG00000137673

MMP7

37.1

4.5E-12

Matrix metallopeptidase 7 (matrilysin, uterine)

ENSG00000130513

GDF15

36.6

3.5E-08

Growth differentiation factor 15

ENSG00000134339

SAA2

36.4

2.6E-12

Serum amyloid A2

ENSG00000163739

CXCL1

33.3

1.6E-13

Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)

ENSG00000117215

PLA2G2D

32.8

2.1E-04

Phospholipase A2, group IID

ENSG00000142224

IL19

32.4

5.3E-07

Interleukin 19

ENSG00000134873

CLDN10

31.8

1.8E-07

Claudin 10

ENSG00000255071

SAA2-SAA4

31.7

3.0E-11

SAA2-SAA4 readthrough

ENSG00000145113

MUC4

31.3

2.6E-11

Mucin 4, cell surface associated