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Table 3 Top 20 down-regulated genes in periodontitis tissues

From: Transcriptome sequencing of gingival biopsies from chronic periodontitis patients reveals novel gene expression and splicing patterns

Ensemble ID

Gene symbol

Fold change

q value

Description

ENSG00000165953

SERPINA12

0.015

1.3E-04

Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12

ENSG00000102891

MT4

0.018

5.5E-04

Metallothionein 4

ENSG00000130600

H19

0.023

4.0E-15

H19, imprinted maternally expressed transcript (non-protein coding)

ENSG00000172867

KRT2

0.023

5.4E-15

Keratin 2

ENSG00000134765

DSC1

0.045

3.6E-11

Desmocollin 1

ENSG00000204538

PSORS1C2

0.046

7.2E-06

Psoriasis susceptibility 1 candidate 2

ENSG00000171446

KRT27

0.047

9.1E-06

Keratin 27

ENSG00000244057

LCE3C

0.053

1.8E-09

Late cornified envelope 3C

ENSG00000161798

AQP5

0.055

1.3E-06

Aquaporin 5

ENSG00000235942

LCE6A

0.057

5.3E-05

Late cornified envelope 6A

ENSG00000188959

C9orf152

0.059

4.2E-04

Chromosome 9 open reading frame 152

ENSG00000196734

LCE1B

0.067

5.4E-06

Late cornified envelope 1B

ENSG00000187223

LCE2D

0.073

1.5E-06

Late cornified envelope 2D

ENSG00000089250

NOS1

0.083

1.4E-07

Nitric oxide synthase 1 (neuronal)

ENSG00000204909

SPINK9

0.085

3.1E-07

Serine peptidase inhibitor, Kazal type 9

ENSG00000130595

TNNT3

0.091

6.7E-06

Troponin T type 3 (skeletal, fast)

ENSG00000110675

ELMOD1

0.091

4.1E-06

ELMO/CED-12 domain containing 1

ENSG00000167768

KRT1

0.091

4.5E-08

Keratin 1

ENSG00000237515

SHISA9

0.097

1.8E-04

Shisa family member 9