Table 3 Functional roles of miRNAs in acute kidney injury
Protective | Pathogenic | Kidney enriched, released from injured kidney tissues | |
|---|---|---|---|
Anti-inflammation  miR-10a  miR-21  miR-26a  miR-126  miR-146a  miR-199a  miR-296 Anti-apoptosis  miR-10a  miR-21  miR-122  miR-126  miR-199a  miR-296  miR-494 Anti-fibrosis  miR-29a  miR-200b  miR-200c | Pro-angiogenesis  miR-126  miR-210  miR-296 Enhancing tubular proliferation  miR-126  miR-296 Cytoskeleton, cell-matrix, cell-cell adhesion, cell trafficking  miR-127a | Pro-inflammation  miR-21  miR-214  miR-494 Pro-apoptosis  miR-24  miR-192  miR-494  miR-687 Pro-fibrosis  miR-21  miR-192  miR-214 | miR-10a miR-30c miR-30d miR-200 family |