Variation of global DNA methylation levels with age and in autistic children

Table 2 Global DNA methylation levels in different male and female age groups

Age groups	Gender	Number	Global DNA methylation (%, mean ± SD)	p value^a
2–25	Male	414	54.99 ± 18.70	0.370
	Female	214	57.42 ± 18.92
26–40	Male	356	67.17 ± 16.56	0.816
	Female	355	67.31 ± 17.29
41–55	Male	151	73.49 ± 15.26	0.010
	Female	182	77.52 ± 13.44
56–75	Male	127	56.42 ± 23.34	0.152
	Female	186	52.37 ± 23.50
75–97	Male	60	40.72 ± 14.14	0.711
	Female	71	41.46 ± 14.20
Overall	Male	1108	60.81 ± 19.86	0.060^b
	Female	1008	62.47 ± 20.81

p < 0.05 is shown in italic font
^a p values using gender as a variable in multivariable linear regression analyses
^b p value for between-gender comparison using Student’s t test

ISSN: 1479-7364