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Fig. 2 | Human Genomics

Fig. 2

From: Novel genetic risk variants for pediatric celiac disease

Fig. 2

a View of the SH3-3/LIM4 binding interface as previously shown by NMR spectroscopy [26]. The Nck2 DH3 domain interface is shown in gray and the PINCH-1 LIM4 domain in green. K249 interacts with E233 and is part of a network connecting R192 of LIM4 and N250 of SH3. b Structural model of the mutant p.K249E and the potential effect in the interactions between SH3 and LIM4

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Human Genomics

ISSN: 1479-7364