Fig. 7
From: Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD
Both cell growth and cell death are altered in ADPKD. NC-ADPKD cells have higher-than-normal expression and C-ADPKD cells have lower-than-normal expression of genes from ‘cell growth’ gene sets. Both NC-ADPKD and C-ADPKD cells have higher-than-normal expression of genes from ‘cell death’ gene sets. We present data as mean ± s.e.m., **P < 0.01, *P < 0.05 (black asterisk is in comparison to NK, gray asterisk is in comparison to NC-ADPKD). Cell Growth Gene Sets: (1) KEGG_CELL_CYCLE, (2) CELL_CYCLE, (3) CELL_CYCLE_CHECKPOINT, (4) CELL_CYCLE_PROCESS, (5) CELL_CYCLE_PHASE, (6) MITOTIC_M_PHASE, (7) MITOTIC_CELL_CYCLE, (8) M_PHASE, (9) MITOSIS. Cell Death Gene Sets: (10) KEGG_APOPTOSIS, (11) APOPTOTIC_PROCESS, (12) PROGRAMMED_CELL_DEATH