From: Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD
 | Size | ES | NES | Normal P value | FDR | FWER P value |
---|---|---|---|---|---|---|
NC-ADPKD/NK, upregulated in NK | ||||||
 KEGG_drug_metabolism_cytochrome_p450 | 42 | 0.8 | 2.17 | 0 | 0 | 0 |
 KEGG_metabolism_of xenobiotics_by_cytochrome p450 | 42 | 0.7 | 2.06 | 0 | 0 | 0.001 |
 KEGG_histidine_metabolism | 22 | 0.8 | 1.94 | 0 | 0.006 | 0.019 |
 KEGG_glutathione_metabolism | 38 | 0.7 | 1.86 | 0 | 0.013 | 0.049 |
 KEGG_fatty_acid_metabolism | 32 | 0.6 | 1.73 | 0.004 | 0.048 | 0.209 |
C-ADPKD/NK, upregulated in C-ADPKD | ||||||
 KEGG_chemokine_signaling_pathway | 144 | −1 | −1.73 | 0 | 0.01 | 0.011 |
 KEGG_axon_guidance | 99 | −1 | −1.68 | 0 | 0.03 | 0.066 |
 KEGG_leukocyte_transendothelial_migration | 86 | −1 | −1.66 | 0.001 | 0.028 | 0.092 |
 GOBP_cell_cell_adhesion | 48 | 0.8 | 1.8 | 0 | 0.001 | 0.001 |
NC-ADPKD/C-ADPKD, upregulated in C-ADPKD | ||||||
 KEGG_leukocyte_transendothelial_migration | 86 | −1 | −1.82 | 0 | 0 | 0 |
 KEGG_chemokine_signaling_pathway | 144 | −1 | −1.74 | 0 | 0.024 | 0.05 |
 KEGG_tight_junction | 101 | −1 | −1.73 | 0 | 0.02 | 0.063 |
 KEGG_axon_guidance | 99 | −1 | −1.73 | 0 | 0.016 | 0.066 |
 GOBP_cell_cell_adhesion | 48 | 0.8 | 1.8 | 0 | 0.007 | 0.008 |