SNP (major/minor allele) | Nearby/associated gene | MAF in Controls Nā=ā462 | Insignificant (nā=ā93) | Single vessel disease (nā=ā121) | Double vessel disease (nā=ā75) | Triple vessel disease (nā=ā70) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MAF | p value | OR (95% CI) | MAF | p value | OR (95% CI) | MAF | p value | OR (95% CI) | MAF | p value | OR (95% CI) | |||
rs17440396:G>A | BUD13 | 0.21 | 0.02 | 3.5āĆā10ā10 | 0.06 (0.02ā0.20) | 0.03 | 1.3āĆā10ā10 | 0.13 (0.06ā0.27) | 0.03 | 2.3āĆā10ā07 | 0.13 (0.05ā0.32) | 0.04 | 2.1āĆā10ā06 | 0.15 (0.06ā0.37) |
rs10488699:G>A | 0.20 | 0.26 | 0.040 | 1.47 (1.02ā2.13) | Ā | Ā | Ā | Ā | Ā | Ā | 0.27 | 0.042 | 1.55 (1.01ā2.35) | |
rs664059:C>T | 0.30 | Ā | Ā | Ā | 0.38 | 0.017 | 1.43 (1.06ā1.92) | Ā | Ā | Ā | 0.39 | 0.042 | 1.47 (1.01ā2.13) | |
rs6589566:A>G | ZPR1 | 0.25 | 0.43 | 1.5āĆā10ā06 | 2.25 (1.61ā3.14) | 0.37 | 0.0005 | 1.71 (1.26ā2.33) | 0.42 | 1.9āĆā10ā05 | 2.18 (1.52ā3.13) | 0.39 | 0.002 | 1.86 (1.25ā2.76) |
rs3741298:A>G | 0.35 | 0.27 | 0.038 | 0.68 (0.48ā0.98) | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | |
rs2075294:G>T | 0.05 | Ā | Ā | Ā | 0.10 | 0.012 | 1.93 (1.15ā3.24) | Ā | Ā | Ā | 0.09 | 0.048 | 1.89 (1.00ā3.59) | |
rs633389:C>T | APOA5-APOA4 | 0.16 | 0.08 | 0.004 | 0.44 (0.25ā0.78) | 0.10 | 0.033 | 0.62 (0.39ā0.97) | 0.07 | 0.003 | 0.38 (0.19ā0.73) | 0.07 | 0.005 | 0.38 (0.19ā0.76) |
rs633867:C>T | 0.06 | Ā | Ā | Ā | 0.10 | 0.020 | 1.81 (1.09ā2.99) | Ā | Ā | Ā | Ā | Ā | Ā | |
rs11600380:T>C | 0.31 | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | 0.22 | 0.030 | 0.62 (0.41ā0.96) | |
rs1263163:G>A | 0.21 | Ā | Ā | Ā | Ā | Ā | Ā | 0.11 | 0.009 | 0.50 (0.30ā0.85) | 0.10 | 0.004 | 0.44 (0.25ā0.78) | |
rs625524:G>A | 0.05 | 0.10 | 0.006 | 2.21 (1.24ā3.92) | Ā | Ā | Ā | Ā | Ā | Ā | 0.01 | 0.028 | 0.15 (0.02ā1.07) | |
rs1263171:G>A | 0.43 | Ā | Ā | Ā | Ā | Ā | Ā | 0.53 | 0.029 | 1.47 (1.04ā2.08) | 0.55 | 0.008 | 1.62 (1.13ā2.32) | |
rs2727793:G>A | 0.37 | Ā | Ā | Ā | Ā | Ā | Ā | 0.45 | 0.044 | 1.43 (1.01ā2.02) | Ā | Ā | Ā | |
rs7396835:C>T | 0.44 | Ā | Ā | Ā | Ā | Ā | Ā | 0.35 | 0.042 | 0.69 (0.48ā0.99) | Ā | Ā | Ā | |
rs2542063:G>A | 0.37 | Ā | Ā | Ā | Ā | Ā | Ā | 0.45 | 0.047 | 1.43 (1.00ā2.02) | Ā | Ā | Ā | |
rs2849165:G>A | 0.36 | 0.20 | 3.1āĆā10ā05 | 0.45 (0.31ā0.66) | 0.22 | 2.9āĆā10ā05 | 0.49 (0.35ā0.69) | 0.21 | 0.0002 | 0.47 (0.31ā0.71) | 0.23 | 0.004 | 0.54 (0.35ā0.83) | |
rs5081:A>T | APOA1 | 0.03 | Ā | Ā | Ā | 0.07 | 0.008 | 2.25 (1.22ā4.16) | Ā | Ā | Ā | Ā | Ā | Ā |
rs5072:C>T | 0.37 | Ā | Ā | Ā | 0.30 | 0.037 | 0.72 (0.53ā0.98) | Ā | Ā | Ā | Ā | Ā | Ā | |
rs632153:G>T | 0.03 | Ā | Ā | Ā | 0.06 | 0.020 | 2.11 (1.11ā4.02) | Ā | Ā | Ā | Ā | Ā | Ā |