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Table 2 Association of variants at 11q23.3 chromosomal region with stable/unstable angina, ACS, and MI categories

From: Genetic determinants of clinical heterogeneity of the coronary artery disease in the population of Hyderabad, India

SNP

Control (nā€‰=ā€‰462)

Angina (nā€‰=ā€‰73)

Acute coronary syndrome (nā€‰=ā€‰165)

Myocardial infarction (nā€‰=ā€‰76)

MAF

MAF

p value

OR (95% CI)

MAF

p value

OR (95% CI)

MAF

p value

OR (95% CI)

rs17440396:G>A

0.21

0.01

1.36ā€‰Ć—ā€‰10āˆ’08

0.05 (0.01ā€“0.21)

0.03

5.15ā€‰Ć—ā€‰10āˆ’14

0.12 (0.06ā€“0.23)

0.03

6.89ā€‰Ć—ā€‰10āˆ’08

0.10 (0.04ā€“0.28)

rs10488699:G>A

0.20

Ā Ā Ā Ā Ā Ā 

0.34

0.0001

2.08 (1.41ā€“3.07)

rs2187126:A>G

0.13

Ā Ā Ā 

0.09

0.025

0.61 (0.39ā€“0.94)

Ā Ā Ā 

rs664059:C>T

0.30

Ā Ā Ā 

0.37

0.029

1.34 (1.03ā€“1.75)

0.41

0.0080

1.61 (1.13ā€“2.30)

rs6589566:A>G

0.25

0.46

5.63ā€‰Ć—ā€‰10āˆ’07

2.56 (1.75ā€“3.73)

0.43

3.36ā€‰Ć—ā€‰10āˆ’09

2.23 (1.70ā€“2.92)

Ā Ā Ā 

rs2075294:G>T

0.05

Ā Ā Ā 

0.08

0.049

1.63 (1.00ā€“2.66)

0.10

0.026

1.97 (1.07ā€“3.62)

rs633389:C>T

0.16

0.06

0.0027

0.36 (0.18ā€“0.72)

0.09

0.0054

0.56 (0.37ā€“0.85)

0.07

0.0053

0.41 (0.22ā€“0.78)

rs633867:C>T

0.06

Ā Ā Ā 

0.09

0.015

1.77 (1.11ā€“2.82)

Ā Ā Ā 

rs1263163:G>A

0.20

Ā Ā Ā Ā Ā Ā 

0.03

1.64ā€‰Ć—ā€‰10āˆ’08

0.11 (0.04ā€“0.29)

rs1263167:A>G

0.09

0.15

0.037

1.70 (1.03ā€“2.82)

Ā Ā Ā Ā Ā Ā 

rs1263171:G>A

0.43

Ā Ā Ā Ā Ā Ā 

0.52

0.040

1.44 (1.02ā€“2.03)

rs2849165:G>A

0.36

Ā Ā Ā 

0.17

1.18ā€‰Ć—ā€‰10āˆ’10

0.35 (0.26ā€“0.49)

0.23

0.0013

0.51 (0.34ā€“0.77)

rs2849176:G>C

0.49

Ā Ā Ā Ā Ā Ā 

0.59

0.032

1.46 (1.03ā€“2.08)

rs5081:A>T

0.03

Ā Ā Ā Ā Ā Ā 

0.07

0.0203

2.28 (1.12ā€“4.65)

rs632153:G>T

0.03

Ā Ā Ā Ā Ā Ā 

0.06

0.035

2.18 (1.04ā€“4.59)

  1. Blank cellā€”not significant
  2. OR odds ratio obtained from logistic regression analysis