Skip to main content

Table 3 P values for variants that were significantly associated after Benjamin Hochberg correction for multiple testing

From: Genetic determinants of clinical heterogeneity of the coronary artery disease in the population of Hyderabad, India

SNP

Control choice

Anatomical category (p values)

Phenotypic severity categories (p values)

Insignificant

SVD

DVD

TVD

ANGINA

ACS

MI

rs17440396:G>A

Total Controls

4.92ā€‰Ć—ā€‰10āˆ’08

1.49ā€‰Ć—ā€‰10āˆ’08

2.02ā€‰Ć—ā€‰10āˆ’05

0.0001

1.43ā€‰Ć—ā€‰10āˆ’06

1.04ā€‰Ć—ā€‰10āˆ’11

6.79ā€‰Ć—ā€‰10āˆ’06

Ā 

Cohort 1

2.36ā€‰Ć—ā€‰10āˆ’06

2.13ā€‰Ć—ā€‰10āˆ’06

0.0005

0.0027

2.54ā€‰Ć—ā€‰10āˆ’05

4.78ā€‰Ć—ā€‰10āˆ’09

0.0001

Ā 

Cohort 2

1.77ā€‰Ć—ā€‰10āˆ’06

2.47ā€‰Ć—ā€‰10āˆ’06

0.0004

0.0021

2.18ā€‰Ć—ā€‰10āˆ’05

1.55ā€‰Ć—ā€‰10āˆ’08

0.0001

rs6589566:A>G

Total Controls

0.0001

0.012

0.0008

Ā 

2.61ā€‰Ć—ā€‰10āˆ’05

1.26ā€‰Ć—ā€‰10āˆ’07

Ā 
Ā 

Cohort 1

0.017

Ā 

0.044

Ā 

0.004

0.0005

Ā 
Ā 

Cohort 2

Ā Ā Ā Ā 

0.036

4.70ā€‰Ć—ā€‰10āˆ’06

Ā 

rs2849165:G>A

Total Controls

0.001

0.001

0.0093

Ā Ā 

7.65ā€‰Ć—ā€‰10āˆ’09

0.026

Ā 

Cohort 1

0.011

0.010

0.044

Ā Ā 

4.30ā€‰Ć—ā€‰10āˆ’07

Ā 
Ā 

Cohort 2

0.015

0.016

Ā Ā Ā 

0.020

Ā 

rs10488699:G>A

Total Controls

Ā Ā Ā Ā Ā Ā 

0.004

Ā 

Cohort 1

Ā Ā Ā Ā Ā Ā 

0.0007

Ā 

Cohort 2

Ā Ā Ā Ā Ā Ā 

0.018

rs1263163:G>A

Total Controls

Ā Ā Ā Ā Ā Ā 

7.83ā€‰Ć—ā€‰10āˆ’06

Ā 

Cohort 1

Ā Ā Ā Ā Ā Ā 

0.0033

Ā 

Cohort 2

Ā Ā Ā Ā Ā Ā 

0.011

rs633389:C>T

Total Controls

Ā Ā 

0.014

Ā Ā Ā Ā 

rs5081:A>T

Cohort 1

Ā 

0.047

Ā Ā Ā Ā Ā 

rs633867:C>T

Cohort 1

Ā 

0.047

Ā Ā Ā Ā Ā 

rs632153:G>T

Cohort 1

Ā 

0.047

Ā Ā Ā Ā Ā 

rs1263171:G>A

Cohort 1

Ā Ā Ā 

0.046

Ā Ā Ā 
  1. Blank cellā€”not significant, total control samples (nā€‰=ā€‰462), cohort 1ā€”nondyslipidemic control cohort (nā€‰=ā€‰270), cohort 2ā€”control cohort devoid of dyslipidemia, diabetes, and hypertension (nā€‰=ā€‰129)