Skip to main content
Fig. 3 | Human Genomics

Fig. 3

From: Transcriptome analysis of bronchoalveolar lavage fluid from children with severe Mycoplasma pneumoniae pneumonia reveals novel gene expression and immunodeficiency

Fig. 3

Model diagram showing primary immunodeficiency. Hematopoietic stem cell (HSC)-derived lymphoid progenitor cells develop into progenitor (pro)-B cells, Pre-B1 cell, Pre-B2 cell, immature B cell, mature B cell, B cell, memory B cell, and plasma cell. The decreased expression of CD79A inhibits the differentiation of Pro-B cell into Pre-B1 cell; the decreased expression of AICDA inhibits the differentiation of mature B cell into B cell; the decreased expression of CD19 and TNFRSF13C inhibits the differentiation of mature B cell into memory B cell and plasma B cell

Back to article page