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Table 3 Comparison of the variant call sensitivity between the Variant Caller plugin and the pipeline developed in-house

From: Development and validation of a variant detection workflow for BRCA1 and BRCA2 genes and its clinical application based on the Ion Torrent technology

  In-house pipeline Variant Caller Ion Torrent Suite
Variants found 574 587
False positives 25 35
Sensitivity 95.64% 94.03%
Reproducibility (NGS only) 94.17% 94.71%
Reproducibility (NGS+Sanger) 100% 100%