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Table 1 Wild-type (+) and c.398delC (−) allele frequencies in Fiumedinisi population

From: A novel RLBP1 gene geographical area-related mutation present in a young patient with retinitis punctata albescens

 

Samples

Allele +

Allele −

Observed

frequency

%

HW-expected frequency

%

Chi-square

p value

+/+

297

594

0

297

99.00

297.01

99.00

0.000

 

+/−

3

3

3

3

1.00

2.99

1.00

0.000

 

−/−

0

0

0

1

0.00

0.01

0.00

0.008

 

Total

300

597

3

300

100.00

300.00

100.00

0.008

0.9306

 

600

1.00

0.01

600

   

(p value) Chisq w 1 df

 
  1. A total of 300 samples were genotyped. Only 0.01% of screened population carries the mutated allele. Chi-square test exhibits a p value = 0.9306 suggesting the presence of the equilibrium’s condition between wild-type and mutated allele in Fiumedinisi population