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Table 3 Fourteen metabolite profiling in the priests

From: Distinct transcriptional and metabolic profiles associated with empathy in Buddhist priests: a pilot study

Metabolites

Priests (n = 10)

Control (n = 10)

Fold change

P value

r

Methionine

5.2E − 03 (4.7–6.0) E − 03

3.7E − 03 (3.1–4.1) E − 03

1.43

0.0002

− 0.761

3-Aminoisobutyric acid (BAIBA)

10.0E − 04 (9.6–13.7) E − 04

2.5E − 04 (2.0–5.4) E − 04

3.06

0.0015

− 0.676

Phenylalanine

2.7E − 02 (2.4–3.0) E − 02

2.2E − 02 (2.1–2.3) E − 02

1.36

0.0029

− 0.642

Choline

8.1E − 03 (7.5–10.2) E − 03

6.7E − 03 (5.6–7.3) E − 03

1.38

0.0052

− 0.608

SDMA (symmetric dimethylarginine)

2.2E − 04 (2.0–2.3) E − 04

2.0E − 04 (1.6–2.0) E − 04

1.20

0.010

− 0.563

2-Aminoadipic acid

3.3E − 04 (2.9–3.8) E − 04

2.0E − 04 (1.7–2.4) E − 03

1.45

0.012

− 0.558

2-Aminobutyric acid (AABA)

8.7E − 03 (7.6–10.7) E − 03

6.8E − 03 (5.9–7.3) E − 03

1.38

0.019

− 0.524

ADMA (asymmetric dimethylarginine)

1.8E − 04 (1.6–2.2) E − 04

1.5E − 04 (1.4–1.7) E − 04

1.20

0.025

− 0.507

Valine

10.3E − 02 (9.4–10.9) E − 02

9.0E − 02 (8.6–10.5) E − 02

1.09

0.023

− 0.507

AC(13:1)

5.9E − 05 (4.5–10.3) E − 05

3.2E − 05 (2.2–4.3) E − 05

1.79

0.027

− 0.491

Creatinine

1.3E − 02 (1.0–2.0) E − 02

0.9E − 02 (0.8–1.1) E − 02

1.64

0.030

− 0.483

Leucine

7.8E − 02 (7.5–9.2) E − 02

7.1E − 02 (6.8–7.8) E − 02

1.14

0.036

− 0.473

Histidine

2.3E − 02 (2.1–2.4) E − 02

2.0E − 02 (1.7–2.3) E − 02

1.10

0.043

− 0.456

Isoleucine

4.5E − 02 (4.2–5.2) E − 02

3.8E − 02 (3.4–4.4) E − 02

1.21

0.043

− 0.456

  1. Values are expressed as median and interquartile range (25–75th percentile). A P value < 0.05 is statistically significant by Mann–Whitney U test. A P value < 0.05 is statistically significant by Mann–Whitney U test. Cohen’s guidelines for the effect sizes (r) for Mann–Whitney U test are that a large effect is 0.5, a medium effect is 0.3, and small effect is 0.1 [28]