Skip to main content
Fig. 5 | Human Genomics

Fig. 5

From: Whole transcriptome analysis of human erythropoietic cells during ontogenesis suggests a role of VEGFA gene as modulator of fetal hemoglobin and pharmacogenomic biomarker of treatment response to hydroxyurea in β-type hemoglobinopathy patients

Fig. 5

In silico analysis of the role of rs3024997 on splicing. For rs3024997 (G > A), the Human Splicing Finder prediction algorithm supports the activation of an intronic cryptic acceptor site and thus, potential alteration of splicing. Yet, the RESCUE ESE, EIEs, PESE Octamers, ESE Finder-SRp40, and ESR Sequences prediction algorithms suggest the creation of an exonic splicing enhancer, probably, with no impact on splicing. The graphic representation of the region confirms individual outcomes per algorithm considered, each one corresponding at a different color and length. For more information on the data, please visit http://www.umd.be/HSF3/technicaltips.html

Back to article page