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Table 2 Unadjusted and adjusted OR for all patients with HTN according to the PAM rs13175330 genotypes

From: The peptidylglycine-α-amidating monooxygenase (PAM) gene rs13175330 A>G polymorphism is associated with hypertension in a Korean population

PAM rs13175330

HTN group (n = 543) OR (95% CI)

p values

Model 1

 A∥ compared with G

1.498 (1.186, 1.892)

0.001

 AA + AG∥ compared with GG

4.192 (1.325, 13.263)

0.015

 AA∥ compared with AG + GG

1.484 (1.154, 1.909)

0.002

Model 2

 A∥ compared with G

1.642 (1.272, 2.121)

< 0.001

 AA + AG∥ compared with GG

7.826 (2.228, 27.484)

0.001

 AA∥ compared with AG + GG

1.607 (1.220, 2.116)

0.001

  1. ∥Reference
  2. CI confidence interval, Model 1 unadjusted, Model 2 adjusted for age, sex, BMI, smoking, and drinking, OR odds ratio, HTN hypertension, PAM peptidylglycine-α-amidating monooxygenase
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Human Genomics

ISSN: 1479-7364