TY - JOUR AU - Willett, W. C. PY - 2002 DA - 2002// TI - Balancing life-style and genomics research for disease prevention JO - Science VL - 296 UR - https://doi.org/10.1126/science.1071055 DO - 10.1126/science.1071055 ID - Willett2002 ER - TY - JOUR AU - Rappaport, S. M. AU - Smith, M. T. PY - 2010 DA - 2010// TI - Epidemiology. Environment and disease risks JO - Science VL - 330 UR - https://doi.org/10.1126/science.1192603 DO - 10.1126/science.1192603 ID - Rappaport2010 ER - TY - JOUR AU - Manrai, A. K. AU - Cui, Y. AU - Bushel, P. R. AU - Hall, M. AU - Karakitsios, S. AU - Mattingly, C. J. AU - Ritchie, M. AU - Schmitt, C. AU - Sarigiannis, D. A. AU - Thomas, D. C. PY - 2017 DA - 2017// TI - Informatics and data analytics to support exposome-based discovery for public health JO - Annu Rev Public Health VL - 38 UR - https://doi.org/10.1146/annurev-publhealth-082516-012737 DO - 10.1146/annurev-publhealth-082516-012737 ID - Manrai2017 ER - TY - JOUR AU - Wild, C. P. PY - 2005 DA - 2005// TI - Complementing the genome with an “exposome”: the outstanding challenge of environmental exposure measurement in molecular epidemiology JO - Cancer Epidemiol Biomark Prev VL - 14 UR - https://doi.org/10.1158/1055-9965.EPI-05-0456 DO - 10.1158/1055-9965.EPI-05-0456 ID - Wild2005 ER - TY - JOUR AU - Miller, G. W. AU - Jones, D. P. PY - 2014 DA - 2014// TI - The nature of nurture: refining the definition of the exposome JO - Toxicol Sci VL - 137 UR - https://doi.org/10.1093/toxsci/kft251 DO - 10.1093/toxsci/kft251 ID - Miller2014 ER - TY - JOUR AU - Vrijheid, M. AU - Slama, R. AU - Robinson, O. AU - Chatzi, L. AU - Coen, M. AU - van den Hazel, P. AU - Thomsen, C. AU - Wright, J. AU - Athersuch, T. J. AU - Avellana, N. PY - 2014 DA - 2014// TI - The human early-life exposome (HELIX): project rationale and design JO - Environ Health Perspect VL - 122 ID - Vrijheid2014 ER - TY - JOUR AU - Vineis, P. AU - Chadeau-Hyam, M. AU - Gmuender, H. AU - Gulliver, J. AU - Herceg, Z. AU - Kleinjans, J. AU - Kogevinas, M. AU - Kyrtopoulos, S. AU - Nieuwenhuijsen, M. AU - Phillips, D. H. PY - 2017 DA - 2017// TI - The exposome in practice: design of the EXPOsOMICS project JO - Int J Hyg Environ Health VL - 220 UR - https://doi.org/10.1016/j.ijheh.2016.08.001 DO - 10.1016/j.ijheh.2016.08.001 ID - Vineis2017 ER - TY - JOUR AU - Dennis, K. K. AU - Marder, E. AU - Balshaw, D. M. AU - Cui, Y. AU - Lynes, M. A. AU - Patti, G. J. AU - Rappaport, S. M. AU - Shaughnessy, D. T. AU - Vrijheid, M. AU - Barr, D. B. PY - 2016 DA - 2016// TI - Biomonitoring in the era of the exposome JO - Environ Health Perspect VL - 125 UR - https://doi.org/10.1289/EHP474 DO - 10.1289/EHP474 ID - Dennis2016 ER - TY - JOUR AU - Dennis, K. K. AU - Auerbach, S. S. AU - Balshaw, D. M. AU - Cui, Y. AU - Fallin, M. D. AU - Smith, M. T. AU - Spira, A. AU - Sumner, S. AU - Miller, G. W. PY - 2016 DA - 2016// TI - The importance of the biological impact of exposure to the concept of the exposome JO - Environ Health Perspect VL - 124 UR - https://doi.org/10.1289/EHP140 DO - 10.1289/EHP140 ID - Dennis2016 ER - TY - JOUR AU - Stingone, J. A. AU - Buck Louis, G. M. AU - Nakayama, S. F. AU - Vermeulen, R. C. AU - Kwok, R. K. AU - Cui, Y. AU - Balshaw, D. M. AU - Teitelbaum, S. L. PY - 2017 DA - 2017// TI - Toward greater implementation of the exposome research paradigm within environmental epidemiology JO - Annu Rev Public Health VL - 38 UR - https://doi.org/10.1146/annurev-publhealth-082516-012750 DO - 10.1146/annurev-publhealth-082516-012750 ID - Stingone2017 ER - TY - JOUR AU - Polderman, T. J. AU - Benyamin, B. AU - de Leeuw, C. A. AU - Sullivan, P. F. AU - van Bochoven, A. AU - Visscher, P. M. AU - Posthuma, D. PY - 2015 DA - 2015// TI - Meta-analysis of the heritability of human traits based on fifty years of twin studies JO - Nat Genet VL - 47 UR - https://doi.org/10.1038/ng.3285 DO - 10.1038/ng.3285 ID - Polderman2015 ER - TY - JOUR AU - Nicholson, G. AU - Rantalainen, M. AU - Maher, A. D. AU - Li, J. V. AU - Malmodin, D. AU - Ahmadi, K. R. AU - Faber, J. H. AU - Hallgrimsdottir, I. B. AU - Barrett, A. AU - Toft, H. PY - 2011 DA - 2011// TI - Human metabolic profiles are stably controlled by genetic and environmental variation JO - Mol Syst Biol VL - 7 UR - https://doi.org/10.1038/msb.2011.57 DO - 10.1038/msb.2011.57 ID - Nicholson2011 ER - TY - JOUR AU - Ghini, V. AU - Saccenti, E. AU - Tenori, L. AU - Assfalg, M. AU - Luchinat, C. PY - 2015 DA - 2015// TI - Allostasis and resilience of the human individual metabolic phenotype JO - J Proteome Res VL - 14 UR - https://doi.org/10.1021/acs.jproteome.5b00275 DO - 10.1021/acs.jproteome.5b00275 ID - Ghini2015 ER - TY - JOUR AU - Maitre, L. AU - Lau, C. E. AU - Vizcaino, E. AU - Robinson, O. AU - Casas, M. AU - Siskos, A. P. AU - Want, E. J. AU - Athersuch, T. AU - Slama, R. AU - Vrijheid, M. PY - 2017 DA - 2017// TI - Assessment of metabolic phenotypic variability in children’s urine using 1H NMR spectroscopy JO - Sci Rep VL - 7 UR - https://doi.org/10.1038/srep46082 DO - 10.1038/srep46082 ID - Maitre2017 ER - TY - JOUR AU - Patel, C. J. AU - Rehkopf, D. H. AU - Leppert, J. T. AU - Bortz, W. M. AU - Cullen, M. R. AU - Chertow, G. M. AU - Ioannidis, J. P. PY - 2013 DA - 2013// TI - Systematic evaluation of environmental and behavioural factors associated with all-cause mortality in the United States national health and nutrition examination survey JO - Int J Epidemiol VL - 42 UR - https://doi.org/10.1093/ije/dyt208 DO - 10.1093/ije/dyt208 ID - Patel2013 ER - TY - JOUR AU - Patel, C. J. AU - Cullen, M. R. AU - Ioannidis, J. P. AU - Butte, A. J. PY - 2012 DA - 2012// TI - Systematic evaluation of environmental factors: persistent pollutants and nutrients correlated with serum lipid levels JO - Int J Epidemiol VL - 41 UR - https://doi.org/10.1093/ije/dys003 DO - 10.1093/ije/dys003 ID - Patel2012 ER - TY - JOUR AU - Patel, C. J. AU - Bhattacharya, J. AU - Butte, A. J. PY - 2010 DA - 2010// TI - An environment-wide association study (EWAS) on type 2 diabetes mellitus JO - PLoS One VL - 5 UR - https://doi.org/10.1371/journal.pone.0010746 DO - 10.1371/journal.pone.0010746 ID - Patel2010 ER - TY - JOUR AU - McGinnis, D. P. AU - Brownstein, J. S. AU - Patel, C. J. PY - 2016 DA - 2016// TI - Environment-wide association study of blood pressure in the National Health and Nutrition Examination Survey (1999–2012) JO - Sci Rep VL - 6 UR - https://doi.org/10.1038/srep30373 DO - 10.1038/srep30373 ID - McGinnis2016 ER - TY - JOUR AU - Ioannidis, J. P. PY - 2016 DA - 2016// TI - Exposure-wide epidemiology: revisiting Bradford Hill JO - Stat Med VL - 35 UR - https://doi.org/10.1002/sim.6825 DO - 10.1002/sim.6825 ID - Ioannidis2016 ER - TY - JOUR AU - Ioannidis, J. P. AU - Tarone, R. AU - McLaughlin, J. K. PY - 2011 DA - 2011// TI - The false-positive to false-negative ratio in epidemiologic studies JO - Epidemiology VL - 22 UR - https://doi.org/10.1097/EDE.0b013e31821b506e DO - 10.1097/EDE.0b013e31821b506e ID - Ioannidis2011 ER - TY - JOUR AU - Patel, C. J. AU - Burford, B. AU - Ioannidis, J. P. PY - 2015 DA - 2015// TI - Assessment of vibration of effects due to model specification can demonstrate the instability of observational associations JO - J Clin Epidemiol VL - 68 UR - https://doi.org/10.1016/j.jclinepi.2015.05.029 DO - 10.1016/j.jclinepi.2015.05.029 ID - Patel2015 ER - TY - JOUR AU - Patel, C. J. AU - Manrai, A. K. AU - Corona, E. AU - Kohane, I. S. PY - 2017 DA - 2017// TI - Systematic correlation of environmental exposure and physiological and self-reported behaviour factors with leukocyte telomere length JO - Int J Epidemiol VL - 46 ID - Patel2017 ER - TY - JOUR AU - Athersuch, T. J. PY - 2012 DA - 2012// TI - The role of metabolomics in characterizing the human exposome JO - Bioanalysis VL - 4 UR - https://doi.org/10.4155/bio.12.211 DO - 10.4155/bio.12.211 ID - Athersuch2012 ER - TY - JOUR AU - Athersuch, T. PY - 2016 DA - 2016// TI - Metabolome analyses in exposome studies: profiling methods for a vast chemical space JO - Arch Biochem Biophys VL - 589 UR - https://doi.org/10.1016/j.abb.2015.10.007 DO - 10.1016/j.abb.2015.10.007 ID - Athersuch2016 ER - TY - JOUR AU - Athersuch, T. J. AU - Keun, H. C. PY - 2015 DA - 2015// TI - Metabolic profiling in human exposome studies JO - Mutagenesis VL - 30 ID - Athersuch2015 ER - TY - JOUR AU - Dona, A. C. AU - Jimenez, B. AU - Schafer, H. AU - Humpfer, E. AU - Spraul, M. AU - Lewis, M. R. AU - Pearce, J. T. AU - Holmes, E. AU - Lindon, J. C. AU - Nicholson, J. K. PY - 2014 DA - 2014// TI - Precision high-throughput proton NMR spectroscopy of human urine, serum, and plasma for large-scale metabolic phenotyping JO - Anal Chem VL - 86 UR - https://doi.org/10.1021/ac5025039 DO - 10.1021/ac5025039 ID - Dona2014 ER - TY - JOUR AU - Lewis, M. R. AU - Pearce, J. T. AU - Spagou, K. AU - Green, M. AU - Dona, A. C. AU - Yuen, A. H. AU - David, M. AU - Berry, D. J. AU - Chappell, K. AU - Horneffer-van der Sluis, V. PY - 2016 DA - 2016// TI - Development and application of ultra-performance liquid chromatography-TOF MS for precision large scale urinary metabolic phenotyping JO - Anal Chem VL - 88 UR - https://doi.org/10.1021/acs.analchem.6b01481 DO - 10.1021/acs.analchem.6b01481 ID - Lewis2016 ER - TY - JOUR AU - Jones, D. P. PY - 2016 DA - 2016// TI - Sequencing the exposome: a call to action JO - Tox Rep VL - 3 ID - Jones2016 ER - TY - STD TI - Walker DI, Go YM, Liu K, Pennell KD, Jones DP. Population screening for biological and environmental properties of the human metabolic phenotype: implications for personalized medicine. In: Holmes E, Nicholson JK, Darzi AW, Lindon JC, editors. Metabolic Phenotyping in personalized and public healthcare. London: Elsevier; 2016. p. 167–211. ID - ref29 ER - TY - JOUR AU - Comisarow, M. B. AU - Marshall, A. G. PY - 1974 DA - 1974// TI - Fourier-transform ion-cyclotron resonance spectroscopy JO - Chem Phys Lett VL - 25 UR - https://doi.org/10.1016/0009-2614(74)89137-2 DO - 10.1016/0009-2614(74)89137-2 ID - Comisarow1974 ER - TY - JOUR AU - Rodgers, R. P. AU - Schaub, T. M. AU - Marshall, A. G. PY - 2005 DA - 2005// TI - Petroleomics: MS returns to its roots JO - Anal Chem VL - 77 UR - https://doi.org/10.1021/ac053302y DO - 10.1021/ac053302y ID - Rodgers2005 ER - TY - JOUR AU - Johnson, J. M. AU - Strobel, F. H. AU - Reed, M. AU - Pohl, J. AU - Jones, D. P. PY - 2008 DA - 2008// TI - A rapid LC-FTMS method for the analysis of cysteine, cystine and cysteine/cystine steady-state redox potential in human plasma JO - Clin Chim Acta VL - 396 UR - https://doi.org/10.1016/j.cca.2008.06.020 DO - 10.1016/j.cca.2008.06.020 ID - Johnson2008 ER - TY - JOUR AU - Hu, Q. AU - Noll, R. J. AU - Li, H. AU - Makarov, A. AU - Hardman, M. AU - Graham Cooks, R. PY - 2005 DA - 2005// TI - The Orbitrap: a new mass spectrometer JO - J Mass Spectrom VL - 40 UR - https://doi.org/10.1002/jms.856 DO - 10.1002/jms.856 ID - Hu2005 ER - TY - JOUR AU - Go, Y. M. AU - Walker, D. I. AU - Liang, Y. AU - Uppal, K. AU - Soltow, Q. A. AU - Tran, V. AU - Strobel, F. AU - Quyyumi, A. A. AU - Ziegler, T. R. AU - Pennell, K. D. PY - 2015 DA - 2015// TI - Reference standardization for mass spectrometry and high-resolution metabolomics applications to exposome research JO - Toxicol Sci VL - 148 UR - https://doi.org/10.1093/toxsci/kfv198 DO - 10.1093/toxsci/kfv198 ID - Go2015 ER - TY - JOUR AU - Rappaport, S. M. AU - Barupal, D. K. AU - Wishart, D. AU - Vineis, P. AU - Scalbert, A. PY - 2014 DA - 2014// TI - The blood exposome and its role in discovering causes of disease JO - Environ Health Perspect VL - 122 ID - Rappaport2014 ER - TY - JOUR AU - Walker, D. I. AU - Mallon, C. T. AU - Hopke, P. K. AU - Uppal, K. AU - Go, Y. M. AU - Rohrbeck, P. AU - Pennell, K. D. AU - Jones, D. P. PY - 2016 DA - 2016// TI - Deployment-associated exposure surveillance with high-resolution metabolomics JO - J Occup Environ Med VL - 58 UR - https://doi.org/10.1097/JOM.0000000000000768 DO - 10.1097/JOM.0000000000000768 ID - Walker2016 ER - TY - JOUR AU - Uppal, K. AU - Walker, D. I. AU - Liu, K. AU - Li, S. AU - Go, Y. M. AU - Jones, D. P. PY - 2016 DA - 2016// TI - Computational metabolomics: a framework for the million metabolome JO - Chem Res Toxicol VL - 29 UR - https://doi.org/10.1021/acs.chemrestox.6b00179 DO - 10.1021/acs.chemrestox.6b00179 ID - Uppal2016 ER - TY - JOUR AU - Johnson, J. M. AU - Yu, T. AU - Strobel, F. H. AU - Jones, D. P. PY - 2010 DA - 2010// TI - A practical approach to detect unique metabolic patterns for personalized medicine JO - Analyst VL - 135 UR - https://doi.org/10.1039/c0an00333f DO - 10.1039/c0an00333f ID - Johnson2010 ER - TY - JOUR AU - Warth, B. AU - Spangler, S. AU - Fang, M. AU - Johnson, C. H. AU - Forsberg, E. M. AU - Granados, A. AU - Martin, R. L. AU - Domingo-Almenara, X. AU - Huan, T. AU - Rinehart, D. PY - 2017 DA - 2017// TI - Exposome-scale investigations guided by global metabolomics, pathway analysis, and cognitive computing JO - Anal Chem VL - 89 UR - https://doi.org/10.1021/acs.analchem.7b02759 DO - 10.1021/acs.analchem.7b02759 ID - Warth2017 ER - TY - JOUR AU - Soltow, Q. A. AU - Strobel, F. H. AU - Mansfield, K. G. AU - Wachtman, L. AU - Park, Y. AU - Jones, D. P. PY - 2013 DA - 2013// TI - High-performance metabolic profiling with dual chromatography-Fourier-transform mass spectrometry (DC-FTMS) for study of the exposome JO - Metabolomics VL - 9 UR - https://doi.org/10.1007/s11306-011-0332-1 DO - 10.1007/s11306-011-0332-1 ID - Soltow2013 ER - TY - JOUR AU - Liu, K. H. AU - Walker, D. I. AU - Uppal, K. AU - Tran, V. AU - Rohrbeck, P. AU - Mallon, T. M. AU - Jones, D. P. PY - 2016 DA - 2016// TI - High-resolution metabolomics assessment of military personnel: evaluating analytical strategies for chemical detection JO - J Occup Environ Med VL - 58 UR - https://doi.org/10.1097/JOM.0000000000000773 DO - 10.1097/JOM.0000000000000773 ID - Liu2016 ER - TY - JOUR AU - Yu, T. AU - Park, Y. AU - Johnson, J. M. AU - Jones, D. P. PY - 2009 DA - 2009// TI - apLCMS—adaptive processing of high-resolution LC/MS data JO - Bioinformatics VL - 25 UR - https://doi.org/10.1093/bioinformatics/btp291 DO - 10.1093/bioinformatics/btp291 ID - Yu2009 ER - TY - JOUR AU - Libiseller, G. AU - Dvorzak, M. AU - Kleb, U. AU - Gander, E. AU - Eisenberg, T. AU - Madeo, F. AU - Neumann, S. AU - Trausinger, G. AU - Sinner, F. AU - Pieber, T. AU - Magnes, C. PY - 2015 DA - 2015// TI - IPO: a tool for automated optimization of XCMS parameters JO - BMC Bioinform VL - 16 UR - https://doi.org/10.1186/s12859-015-0562-8 DO - 10.1186/s12859-015-0562-8 ID - Libiseller2015 ER - TY - JOUR AU - Uppal, K. AU - Soltow, Q. A. AU - Strobel, F. H. AU - Pittard, W. S. AU - Gernert, K. M. AU - Yu, T. AU - Jones, D. P. PY - 2013 DA - 2013// TI - xMSanalyzer: automated pipeline for improved feature detection and downstream analysis of large-scale, non-targeted metabolomics data JO - BMC Bioinform VL - 14 UR - https://doi.org/10.1186/1471-2105-14-15 DO - 10.1186/1471-2105-14-15 ID - Uppal2013 ER - TY - JOUR AU - Uppal, K. AU - Walker, D. I. AU - Jones, D. P. PY - 2017 DA - 2017// TI - xMSannotator: an R package for network-based annotation of high-resolution metabolomics data JO - Anal Chem VL - 89 UR - https://doi.org/10.1021/acs.analchem.6b01214 DO - 10.1021/acs.analchem.6b01214 ID - Uppal2017 ER - TY - JOUR AU - Kanehisa, M. AU - Goto, S. AU - Sato, Y. AU - Kawashima, M. AU - Furumichi, M. AU - Tanabe, M. PY - 2014 DA - 2014// TI - Data, information, knowledge and principle: back to metabolism in KEGG JO - Nucleic Acids Res VL - 42 UR - https://doi.org/10.1093/nar/gkt1076 DO - 10.1093/nar/gkt1076 ID - Kanehisa2014 ER - TY - JOUR AU - Xia, J. AU - Mandal, R. AU - Sinelnikov, I. V. AU - Broadhurst, D. AU - Wishart, D. S. PY - 2012 DA - 2012// TI - MetaboAnalyst 2.0—a comprehensive server for metabolomic data analysis JO - Nucleic Acids Res VL - 40 UR - https://doi.org/10.1093/nar/gks374 DO - 10.1093/nar/gks374 ID - Xia2012 ER - TY - JOUR AU - Li, S. AU - Park, Y. AU - Duraisingham, S. AU - Strobel, F. H. AU - Khan, N. AU - Soltow, Q. A. AU - Jones, D. P. AU - Pulendran, B. PY - 2013 DA - 2013// TI - Predicting network activity from high throughput metabolomics JO - PLoS Comput Biol VL - 9 UR - https://doi.org/10.1371/journal.pcbi.1003123 DO - 10.1371/journal.pcbi.1003123 ID - Li2013 ER - TY - JOUR AU - Walker, D. I. AU - Uppal, K. AU - Zhang, L. AU - Vermeulen, R. AU - Smith, M. AU - Hu, W. AU - Purdue, M. P. AU - Tang, X. AU - Reiss, B. AU - Kim, S. PY - 2016 DA - 2016// TI - High-resolution metabolomics of occupational exposure to trichloroethylene JO - Int J Epidemiol VL - 45 UR - https://doi.org/10.1093/ije/dyw218 DO - 10.1093/ije/dyw218 ID - Walker2016 ER - TY - JOUR AU - Smith, C. A. AU - O'Maille, G. AU - Want, E. J. AU - Qin, C. AU - Trauger, S. A. AU - Brandon, T. R. AU - Custodio, D. E. AU - Abagyan, R. AU - Siuzdak, G. PY - 2005 DA - 2005// TI - METLIN—a metabolite mass spectral database JO - Ther Drug Monit VL - 27 UR - https://doi.org/10.1097/01.ftd.0000179845.53213.39 DO - 10.1097/01.ftd.0000179845.53213.39 ID - Smith2005 ER - TY - JOUR AU - Wishart, D. S. AU - Jewison, T. AU - Guo, A. C. AU - Wilson, M. AU - Knox, C. AU - Liu, Y. F. AU - Djoumbou, Y. AU - Mandal, R. AU - Aziat, F. AU - Dong, E. PY - 2013 DA - 2013// TI - HMDB 3.0—The Human Metabolome Database in 2013 JO - Nucleic Acids Res VL - 41 UR - https://doi.org/10.1093/nar/gks1065 DO - 10.1093/nar/gks1065 ID - Wishart2013 ER - TY - JOUR AU - Kanehisa, M. AU - Goto, S. AU - Sato, Y. AU - Furumichi, M. AU - Tanabe, M. PY - 2012 DA - 2012// TI - KEGG for integration and interpretation of large-scale molecular data sets JO - Nucleic Acids Res VL - 40 UR - https://doi.org/10.1093/nar/gkr988 DO - 10.1093/nar/gkr988 ID - Kanehisa2012 ER - TY - STD TI - Trupp M, Altman T, Fulcher CA, Caspi R, Krummenacker M, Paley S, Karp PD. Beyond the genome (BTG) is a (PGDB) pathway genome database: HumanCyc. Genome Biol. 2010;11:O12. ID - ref53 ER - TY - JOUR AU - Zamboni, N. AU - Saghatelian, A. AU - Patti, G. J. PY - 2015 DA - 2015// TI - Defining the metabolome: size, flux, and regulation JO - Mol Cell VL - 58 UR - https://doi.org/10.1016/j.molcel.2015.04.021 DO - 10.1016/j.molcel.2015.04.021 ID - Zamboni2015 ER - TY - JOUR AU - Paglia, G. AU - Astarita, G. PY - 2017 DA - 2017// TI - Metabolomics and lipidomics using traveling-wave ion mobility mass spectrometry JO - Nat Protoc VL - 12 UR - https://doi.org/10.1038/nprot.2017.013 DO - 10.1038/nprot.2017.013 ID - Paglia2017 ER - TY - JOUR AU - Baker, E. S. AU - Schymanski, E. L. AU - Renslow, R. S. AU - Thomas, D. G. AU - Causon, T. J. AU - Webb, I. K. AU - Hann, S. AU - Smith, R. D. AU - Teeguarden, J. G. PY - 2017 DA - 2017// TI - Integrating ion mobility spectrometry into mass spectrometry-based exposome measurements: what can it add and how far can it go? JO - Bioanalysis VL - 9 UR - https://doi.org/10.4155/bio-2016-0244 DO - 10.4155/bio-2016-0244 ID - Baker2017 ER - TY - JOUR AU - Castle, A. L. AU - Fiehn, O. AU - Kaddurah-Daouk, R. AU - Lindon, J. C. PY - 2006 DA - 2006// TI - Metabolomics standards workshop and the development of international standards for reporting metabolomics experimental results JO - Brief Bioinform VL - 7 UR - https://doi.org/10.1093/bib/bbl008 DO - 10.1093/bib/bbl008 ID - Castle2006 ER - TY - STD TI - Uppal K, Ma C, Go YM, Jones DP. xMWAS: a data-driven integration and differential network analysis tool. Bioinformatics. 2017:btx656. ID - ref58 ER - TY - JOUR AU - Roede, J. R. AU - Uppal, K. AU - Park, Y. AU - Tran, V. AU - Jones, D. P. PY - 2014 DA - 2014// TI - Transcriptome-metabolome wide association study (TMWAS) of maneb and paraquat neurotoxicity reveals network level interactions in toxicologic mechanism JO - Toxicol Rep VL - 1 UR - https://doi.org/10.1016/j.toxrep.2014.07.006 DO - 10.1016/j.toxrep.2014.07.006 ID - Roede2014 ER - TY - JOUR AU - Cribbs, S. K. AU - Uppal, K. AU - Li, S. AU - Jones, D. P. AU - Huang, L. AU - Tipton, L. AU - Fitch, A. AU - Greenblatt, R. M. AU - Kingsley, L. AU - Guidot, D. M. PY - 2016 DA - 2016// TI - Correlation of the lung microbiota with metabolic profiles in bronchoalveolar lavage fluid in HIV infection JO - Microbiome VL - 4 UR - https://doi.org/10.1186/s40168-016-0147-4 DO - 10.1186/s40168-016-0147-4 ID - Cribbs2016 ER - TY - JOUR AU - Chandler, J. D. AU - Hu, X. AU - Ko, E. J. AU - Park, S. AU - Lee, Y. T. AU - Orr, M. AU - Fernandes, J. AU - Uppal, K. AU - Kang, S. M. AU - Jones, D. P. AU - Go, Y. M. PY - 2016 DA - 2016// TI - Metabolic pathways of lung inflammation revealed by high-resolution metabolomics (HRM) of H1N1 influenza virus infection in mice JO - Am J Physiol Regul Integr Comp Physiol VL - 311 UR - https://doi.org/10.1152/ajpregu.00298.2016 DO - 10.1152/ajpregu.00298.2016 ID - Chandler2016 ER - TY - JOUR AU - Lee, D. S. AU - Park, J. AU - Kay, K. A. AU - Christakis, N. A. AU - Oltvai, Z. N. AU - Barabasi, A. L. PY - 2008 DA - 2008// TI - The implications of human metabolic network topology for disease comorbidity JO - Proc Natl Acad Sci U S A VL - 105 UR - https://doi.org/10.1073/pnas.0802208105 DO - 10.1073/pnas.0802208105 ID - Lee2008 ER - TY - JOUR AU - Sturmberg, J. P. AU - Bennett, J. M. AU - Martin, C. M. AU - Picard, M. PY - 2017 DA - 2017// TI - ‘Multimorbidity’ as the manifestation of network disturbances JO - J Eval Clin Pract VL - 23 UR - https://doi.org/10.1111/jep.12587 DO - 10.1111/jep.12587 ID - Sturmberg2017 ER - TY - JOUR AU - Sturla, S. J. AU - Boobis, A. R. AU - FitzGerald, R. E. AU - Hoeng, J. AU - Kavlock, R. J. AU - Schirmer, K. AU - Whelan, M. AU - Wilks, M. F. AU - Peitsch, M. C. PY - 2014 DA - 2014// TI - Systems toxicology: from basic research to risk assessment JO - Chem Res Toxicol VL - 27 UR - https://doi.org/10.1021/tx400410s DO - 10.1021/tx400410s ID - Sturla2014 ER - TY - JOUR AU - Ioannidis, J. P. AU - Loy, E. Y. AU - Poulton, R. AU - Chia, K. S. PY - 2009 DA - 2009// TI - Researching genetic versus nongenetic determinants of disease: a comparison and proposed unification JO - Sci Transl Med VL - 1 UR - https://doi.org/10.1126/scitranslmed.3000247 DO - 10.1126/scitranslmed.3000247 ID - Ioannidis2009 ER - TY - JOUR AU - Patel, C. J. AU - Ji, J. AU - Sundquist, J. AU - Ioannidis, J. P. AU - Sundquist, K. PY - 2016 DA - 2016// TI - Systematic assessment of pharmaceutical prescriptions in association with cancer risk: a method to conduct a population-wide medication-wide longitudinal study JO - Sci Rep VL - 6 UR - https://doi.org/10.1038/srep31308 DO - 10.1038/srep31308 ID - Patel2016 ER - TY - JOUR AU - Patel, C. J. AU - Ioannidis, J. P. PY - 2014 DA - 2014// TI - Placing epidemiological results in the context of multiplicity and typical correlations of exposures JO - J Epidemiol Community Health VL - 68 UR - https://doi.org/10.1136/jech-2014-204195 DO - 10.1136/jech-2014-204195 ID - Patel2014 ER - TY - STD TI - Patel CJ, Manrai AK. Development of exposome correlation globes to map out environment-wide associations. In: Altman RB, Dunker AK, Hunter L, Ritchie MD, Murray TA, Klein TE, editors. Biocomputing 2015 Proceedings of the Pacific Symposium: Kohala Coast, Hawaii, USA: 4-8 January 2015. New Jersey: World Scientific Pub Co Inc.; 2015. p. 231-42. ID - ref68 ER - TY - STD TI - Patel CJ, Pho N, McDuffie M, Easton-Marks J, Kothan C, Kohane IS, Avillach P. A database of human exposomes and phenomes from the US National Health and Nutrition Examination Survey. Sci Data. 2017;3. ID - ref69 ER - TY - JOUR AU - Patel, C. J. AU - Ioannidis, J. P. PY - 2014 DA - 2014// TI - Studying the elusive environment in large scale JO - JAMA VL - 311 UR - https://doi.org/10.1001/jama.2014.4129 DO - 10.1001/jama.2014.4129 ID - Patel2014 ER -