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Fig. 2 | Human Genomics

Fig. 2

From: Correlation of gene expression and associated mutation profiles of APOBEC3A, APOBEC3B, REV1, UNG, and FHIT with chemosensitivity of cancer cell lines to drug treatment

Fig. 2

a–e Histograms and density functions showing the distributions of expression of the five candidate genes in the cell lines. a APOBEC3A. b APOBEC3B. c REV1. d UNG. e FHIT. Horizontal scale represents log2-transformed gene expression values. The left vertical scale represents cell line counts, whereas the right vertical scale represents density values. f A scatterplot of APOBEC3B vs APOBEC3A expression in 1012 cell lines from the CCLE microarray expression dataset which shows the copy number status of the APOBEC3B gene according to the CCLE data [33]. Cell lines with log2(normalized ratio of APOBEC3B copy number estimate) ≥ − 0.75 are shown in blue, whereas those with log2(normalized ratio of APOBEC3B copy number estimate) < − 0.75 are shown in red

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Human Genomics

ISSN: 1479-7364