Skip to main content
Fig. 3 | Human Genomics

Fig. 3

From: Correlation of gene expression and associated mutation profiles of APOBEC3A, APOBEC3B, REV1, UNG, and FHIT with chemosensitivity of cancer cell lines to drug treatment

Fig. 3

a–c Overall motif counts in different cancer types and across all cell lines (pan-cancer analysis). The y axis is presented on the log10 scale. a T(C>K)W motif counts. b T(C>D)R motif counts. c T(C>D)D motif counts. d–f Numbers of distinct, not overlapping 5/1000 kataegis clusters with ≥ 5 motifs on the same genome strand per 1000 bp in different cancer types and in the pan-cancer dataset. d T(C>K)W motif counts. e T(C>D)R motif counts. f T(C>D)D motif counts. Horizontal middle bars show the mean for each cancer category. Vertical bars show mean ± standard deviation. Negative values of (mean − standard deviation) in d and e were truncated at 0. Cancer categories with no vertical columns had no predicted kataegis clusters (d–f) and/or too few cell lines to compute the standard deviation (n = 2 for mesothelioma, a–c)

Back to article page