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Fig. 4 | Human Genomics

Fig. 4

From: Correlation of gene expression and associated mutation profiles of APOBEC3A, APOBEC3B, REV1, UNG, and FHIT with chemosensitivity of cancer cell lines to drug treatment

Fig. 4

Scatterplots of drug sensitivity measures from the GDSC dataset in selected cancer types. a log(IC50) of JQ1 vs log2 of the APOBEC3A gene expression in pancreatic adenocarcinoma cell lines. b log(IC50) of bicalutamide vs the combined length of predicted 5/1000 kataegis clusters with the T(C>D)D motif in breast cancer cell lines. The names of individual breast cancer cell lines are shown. r Pearson’s correlation coefficient

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