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Table 1 MAR/SAR predicted in the ABL gene

From: Oxidative stress-induced chromosome breaks within the ABL gene: a model for chromosome rearrangement in nasopharyngeal carcinoma

Predicted MAR/SAR

AWWRTAANNWWGNNNC (16 bp)

Nucleotide position

AATAAYAA (8 bp)

Nucleotide position

Distance (bp)

Location in exon/intron

1–1

ATTGTAACCATATCTC (C)

26,055–26,070

AATAATAA (C)

26,118–26,125

+ 47

Intron 1

1–2

ATCATAACTTAGCAAC (C)

26,613–26,628

AATAACAA (W)

26,565–26,572

−40

Intron 1

2

AAAAAAATTTTGTACC (C)

29,601–29,616

AATAATAA (C)

29,629–29,636

+ 12

Intron 1

3–1

ATAATAATTATACAAC (C)

80,698–80,713

AATAATAA (W)

80,726–80,733

+ 12

Intron 1

 

AATATAAATAAAGTGC (W)

80,732–80,747

  

Overlap

 

3–2

ATTGTAACTAAGGTTC (C)

81,458–81,473

AATAACAA (C)

81,422–81,429

−28

Intron 1

4

ATAATAATAAAGAGAT (W)

99,259–99,274

AATAATAA (W)

99,261–99,268

Overlap

Intron 1

 

AATATAATCAACTGAC (W)

99,447–99,462

  

− 178

 

5

ATAAAAAGGAAGATTC (W)

105,498–105,513

AATAATAA (C)

105,616–105,623

+ 102

Intron 1

6

AAAAAAAAAAAGACTC (C)

108,315–108,330

AATAATAA (C)

108,484–108,491

+ 153

Intron 1

   

AATAATAA (C)

108,487–108,494

+ 156

 
   

AATAATAA (C)

108,490–108,497

+ 159

 

7

AATGTAACAGAGAGCC (C)

117,122–117,137

AATAACAA (W)

117,343–117,350

+ 205

Intron 1

8

AAAATAAACATATACC (W)

119,757–119,772

AATAATAA (W)

119,739–119,746

− 10

Intron 1

9

AAAGTAAAATTGAAAG (C)

133,546–133,561

AATAACAA (W)

133,810–133,817

+ 248

Intron 1

10

ATTACAAGTTTGGTAC (C)

144,212–144,227

AATAATAA (C)

143,996–144,003

− 208

Intron 3

11

ATAAAAACAAAGAAGC (C)

163,018–163,033

AATAACAA (W)

163,048–163,055

+ 14

Intron 7

12

AAAATAATAATGGCCA (W)

167,856–167,871

AATAATAA (W)

167,858–167,865

Overlap

Intron 10

  1. Nucleotide positions of the MRSs with their sequence composition, relative orientation (C, Crick strand and W, Watson strand), distance between the two sequence elements and location of the MRSs in the exon or intron of the ABL gene are shown. A negative distance indicates that 8 bp sequence element precedes the 16 bp sequence element