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Table 1 MAR/SAR predicted in the ABL gene

From: Oxidative stress-induced chromosome breaks within the ABL gene: a model for chromosome rearrangement in nasopharyngeal carcinoma

Predicted MAR/SAR AWWRTAANNWWGNNNC (16 bp) Nucleotide position AATAAYAA (8 bp) Nucleotide position Distance (bp) Location in exon/intron
1–1 ATTGTAACCATATCTC (C) 26,055–26,070 AATAATAA (C) 26,118–26,125 + 47 Intron 1
1–2 ATCATAACTTAGCAAC (C) 26,613–26,628 AATAACAA (W) 26,565–26,572 −40 Intron 1
2 AAAAAAATTTTGTACC (C) 29,601–29,616 AATAATAA (C) 29,629–29,636 + 12 Intron 1
3–1 ATAATAATTATACAAC (C) 80,698–80,713 AATAATAA (W) 80,726–80,733 + 12 Intron 1
  AATATAAATAAAGTGC (W) 80,732–80,747    Overlap  
3–2 ATTGTAACTAAGGTTC (C) 81,458–81,473 AATAACAA (C) 81,422–81,429 −28 Intron 1
4 ATAATAATAAAGAGAT (W) 99,259–99,274 AATAATAA (W) 99,261–99,268 Overlap Intron 1
  AATATAATCAACTGAC (W) 99,447–99,462    − 178  
5 ATAAAAAGGAAGATTC (W) 105,498–105,513 AATAATAA (C) 105,616–105,623 + 102 Intron 1
6 AAAAAAAAAAAGACTC (C) 108,315–108,330 AATAATAA (C) 108,484–108,491 + 153 Intron 1
    AATAATAA (C) 108,487–108,494 + 156  
    AATAATAA (C) 108,490–108,497 + 159  
7 AATGTAACAGAGAGCC (C) 117,122–117,137 AATAACAA (W) 117,343–117,350 + 205 Intron 1
8 AAAATAAACATATACC (W) 119,757–119,772 AATAATAA (W) 119,739–119,746 − 10 Intron 1
9 AAAGTAAAATTGAAAG (C) 133,546–133,561 AATAACAA (W) 133,810–133,817 + 248 Intron 1
10 ATTACAAGTTTGGTAC (C) 144,212–144,227 AATAATAA (C) 143,996–144,003 − 208 Intron 3
11 ATAAAAACAAAGAAGC (C) 163,018–163,033 AATAACAA (W) 163,048–163,055 + 14 Intron 7
12 AAAATAATAATGGCCA (W) 167,856–167,871 AATAATAA (W) 167,858–167,865 Overlap Intron 10
  1. Nucleotide positions of the MRSs with their sequence composition, relative orientation (C, Crick strand and W, Watson strand), distance between the two sequence elements and location of the MRSs in the exon or intron of the ABL gene are shown. A negative distance indicates that 8 bp sequence element precedes the 16 bp sequence element