TY - JOUR AU - Fan, Xiaowei AU - Ma, Lifeng AU - Zhang, Zhiying AU - Li, Yi AU - Hao, Meng AU - Zhao, Zhipeng AU - Zhao, Yiduo AU - Liu, Fang AU - Liu, Lijun AU - Luo, Xingguang AU - Cai, Peng AU - Li, Yansong AU - Kang, Longli PY - 2018 DA - 2018/07/27 TI - Associations of high-altitude polycythemia with polymorphisms in PIK3CD and COL4A3 in Tibetan populations JO - Human Genomics SP - 37 VL - 12 IS - 1 AB - High-altitude polycythemia (HAPC) is a chronic high-altitude disease that can lead to an increase in the production of red blood cells in the people who live in the plateau, a hypoxia environment, for a long time. The most frequent symptoms of HAPC include headache, dizziness, breathlessness, sleep disorders, and dilation of veins. Although chronic hypoxia is the main cause of HAPC, the fundamental pathophysiologic process and related molecular mechanisms responsible for its development remain largely unclear yet. SN - 1479-7364 UR - https://doi.org/10.1186/s40246-018-0169-z DO - 10.1186/s40246-018-0169-z ID - Fan2018 ER -