Associations of high-altitude polycythemia with polymorphisms in PIK3CD and COL4A3 in Tibetan populations

Fan, Xiaowei; Ma, Lifeng; Zhang, Zhiying; Li, Yi; Hao, Meng; Zhao, Zhipeng; Zhao, Yiduo; Liu, Fang; Liu, Lijun; Luo, Xingguang; Cai, Peng; Li, Yansong; Kang, Longli

doi:10.1186/s40246-018-0169-z

Human Genomics

Table 3 Basic information of candidate SNPs in Tibetan subjects

From: Associations of high-altitude polycythemia with polymorphisms in PIK3CD and COL4A3 in Tibetan populations

SNP_ID	Gene	Alleles A/B	Case (N)			Control (N)			OR (95% CI)	P	P1	P2
SNP_ID	Gene	Alleles A/B	AA	AB	BB	AA	AB	BB	OR (95% CI)	P	P1	P2
rs7518602	PIK3CD	C/T	5	29	36	1	10	19	1.043 (0.438–2.490)	0.612	0.240	0.238
rs7516138	PIK3CD	G/A	11	26	33	3	13	14	1.015 (0.428–2.411)	0.992	0.735	0.733
rs7516214	PIK3CD	G/A	11	26	32	3	13	14	0.992 (0.416–2.366)	0.982	0.688	0.691
rs11805716	PIK3CD	T/C	15	27	17	6	8	13	1.061 (0.416–2.718)	0.555	0.207	0.206
rs11806839	PIK3CD	G/C	5	7	4	2	9	3	1.205 (0.270–5.393)	0.893	0.593	0.612
rs79190623	PIK3CD	C/T	58	10	1	18	11	1	0.862 (0.349–2.106)	0.081	0.018	0.018
rs72633866	PIK3CD	G/A	57	8	1	25	2	0	1.071 (0.434–2.656)	0.791	0.366	0.367
rs2230735	PIK3CD	A/G	59	10	1	17	12	1	0.844 (0.337–2.079)	0.046	0.008	0.008
rs182137610	PIK3CD	A/C	57	10	1	18	9	1	0.764 (0.301–1.897)	0.150	0.050	0.045
rs188191807	PIK3CD	G/A	53	5	1	22	5	0	0.685 (0.266–1.726)	0.791	0.454	0.396
rs28730671	PIK3CD	C/T	63	6	1	19	10	1	0.821 (0.324–2.035)	0.046	0.007	0.007
rs111888887	PIK3CD	T/C	61	6	1	21	8	1	0.906 (0.368–2.205)	0.130	0.034	0.034
rs9430220	PIK3CD	T/C	29	34	5	12	14	4	0.940 (0.395–2.234)	0.851	0.536	0.535
rs28730674	PIK3CD	A/G	63	6	1	19	10	1	0.821 (0.324–2.035)	0.046	0.007	0.007
rs371870925	PIK3CD	T/C	64	4	1	20	9	1	0.812 (0.320–2.017)	0.046	0.007	0.007
rs199962152	PIK3CD	A/G	58	4	1	19	6	1	0.685 (0.256–1.766)	0.146	0.045	0.040
rs77571929	PIK3CD	T/C	63	5	1	19	10	1	0.814 (0.320–2.024)	0.046	0.005	0.005
rs117226273	PIK3CD	G/T	63	6	1	19	10	1	0.821 (0.324–2.035)	0.046	0.007	0.007
rs28730676	PIK3CD	T/C	63	6	1	19	10	1	0.821 (0.324–2.035)	0.046	0.007	0.007
rs10864435	PIK3CD	C/T	55	15	0	25	4	1	1.011 (0.423–2.417)	0.992	0.879	0.878
rs28730677	PIK3CD	G/A	63	6	1	19	10	1	0.821 (0.324–2.035)	0.046	0.007	0.007
rs10178458	COL4A3	T/C	4	21	45	4	7	19	1.026 (0.432–2.442)	0.851	0.539	0.537
rs6436669	COL4A3	A/G	4	21	45	4	7	19	1.026 (0.432–2.442)	0.851	0.539	0.537
rs80109666	COL4A3	G/A	60	9	1	28	2	0	1.070 (0.449–2.559)	0.655	0.271	0.267
rs55703767	COL4A3	G/T	47	21	2	18	8	4	0.990 (0.415–2.360)	0.524	0.184	0.184
rs10205042	COL4A3	C/T	0	23	47	4	8	18	1.017 (0.425–2.437)	0.305	0.102	0.102
rs34505188	COL4A3	G/A	42	20	8	10	14	6	0.948 (0.390–2.292)	0.115	0.028	0.028
rs11677877	COL4A3	A/G	42	21	7	10	13	7	0.941 (0.385–2.290)	0.070	0.013	0.013
rs34019152	COL4A3	G/A	42	20	8	10	13	7	0.928 (0.380–2.254)	0.081	0.018	0.018
rs28381984	COL4A3	C/T	24	39	7	23	6	1	0.761 (0.294–1.928)	0.035	0.001	0.001

The abbreviations were the same as Table 2

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